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Application of Sub- and Supercritical Freons in Xenogenic Bone Matrix Processing


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Abstract

Sub- and supercritical freons can be successfully used in the bone matrix cleaning process. In the case of freon R22 the duration of bone matrix cleaning significantly decreases as compared to the same procedure with supercritical carbon dioxide. Freons R23, R134 and R407c which do not contain chlorine atoms are almost ineffective in this process.

About the authors

D. Yu. Zalepugin

State Plant of Medicinal Drugs

Author for correspondence.
Email: zaledmit@gmail.com
Russian Federation, Moscow, 111024

N. A. Tilkunova

State Plant of Medicinal Drugs

Email: zaledmit@gmail.com
Russian Federation, Moscow, 111024

I. V. Chernyshova

State Plant of Medicinal Drugs

Email: zaledmit@gmail.com
Russian Federation, Moscow, 111024

M. I. Vlasov

State Plant of Medicinal Drugs

Email: zaledmit@gmail.com
Russian Federation, Moscow, 111024

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