Nuclear Magnetic Ions of Magnesium, Calcium, and Zinc as a Powerful and Universal Means for Killing Cancer Cells
- Authors: Kuznetsov D.A.1,2, Buchachenko A.L.2,3,4,5
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Affiliations:
- Pirogoff Russian National Research Medical University
- Institute of Chemical Physics
- Institute of Problems of Chemical Physics
- Scientific Center of the Russian Academy of Sciences
- Yaroslavl’ State University
- Issue: Vol 12, No 4 (2018)
- Pages: 690-694
- Section: Chemical Physics of Biological Processes
- URL: https://journal-vniispk.ru/1990-7931/article/view/200878
- DOI: https://doi.org/10.1134/S1990793118040267
- ID: 200878
Cite item
Abstract
Magnetic isotope effect controls enzymatic DNA synthesis and strongly, by 2–3 times, suppresses catalytic activity of polymerases and increases even more strongly, by 20–50 times, the mortality of cancer cells. Catalyzing ions 25Mg2+, 43Ca2+, and 67Zn2+ carrying magnetic nuclei are shown to efficiently kill cancer cells. The advantage of these ions for practical medicine is that being injected in blood they are captured selectively and almost exclusively by cancer cells inducing their death. The healthy cells capture these ions much less efficiently (perhaps due to the lower penetrability of their membranes) and are not vulnerable to these ions in comparison with cancer cells. Of course, penetrability of cells is identical for magnetic and nonmagnetic ions, but only the former kill cancer cells.
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About the authors
D. A. Kuznetsov
Pirogoff Russian National Research Medical University; Institute of Chemical Physics
Email: alb9397128@yandex.ru
Russian Federation, Moscow, 119997; Moscow, 119991
A. L. Buchachenko
Institute of Chemical Physics; Institute of Problems of Chemical Physics; Scientific Center of the Russian Academy of Sciences; Yaroslavl’ State University
Author for correspondence.
Email: alb9397128@yandex.ru
Russian Federation, Moscow, 119991; Chernogolovka, 142432; Chernogolovka, 142432; Yaroslavl’, 150000
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