Email this article Persistent hyperplastic primary vitreous syndrome and features of congenital cataract surgery and aphakia correction
- Authors: Kruglova T.B.1, Egiyan N.S.1
-
Affiliations:
- Helmholtz National Medical Research Center of Eye Diseases
- Issue: Vol 19, No 3 (2024)
- Pages: 139-145
- Section: Original study article
- URL: https://journal-vniispk.ru/1993-1859/article/view/273452
- DOI: https://doi.org/10.17816/rpoj634839
- ID: 273452
Cite item
Open Access
Access granted
Subscription Access
Abstract
Persistent hyperplastic primary vitreous (PHPV) is a rare, predominantly unilateral congenital eye pathology associated with delayed reverse development of the hyaloid artery and embryonic vascular membrane of the lens and often co-occurs with congenital cataract and microphthalmos.
AIM: To develop optimal differentiated tactics for surgical treatment and correction of aphakia in congenital cataract extraction in children with PHPV.
MATERIAL AND METHODS: Fifty-two children (54 eyes) aged 3–10 months to 1 year and 8 months with unilateral (50 eyes, 92.6%) and bilateral (4 eyes, 7.4%) congenital cataract with PHPV were studied. Grade I microphthalmos was noted in 15 eyes; grade II microphthalmos in 9 eyes; a fibrous cord coming from the optic nerve disk in 49 eyes; a persistent vascular bag of the lens in 12 eyes; posterior synechiae in 9 eyes; a retrolental membrane with vessels and elongated ciliary processes fixed to it, occupying 1/8 to 1/2 of the area of the posterior chamber of the eye in 16 eyes; and a dislocation of the lens in 2 eyes. The children were comprehensively examined by biomicroscopy, ophthalmoscopy, biometrics, tonometry, keratorefractometry, B-scanning, ultrasound biomicroscopy, and color Doppler mapping.
RESULTS: The clinical picture of eyes with congenital cataract in three groups of children, united by the severity of clinical manifestations of PHPV, was analyzed. Differentiated microsurgical tactics for the removal of congenital cataracts and indications for implantation of intraocular lenses are described.
CONCLUSION: The clinical picture of PHPV in children with congenital cataracts is characterized by pronounced polymorphism, indicating the need for a differentiated approach in determining the optimal timing of surgery, surgical tactics, and method of aphakia correction.
Full Text
##article.viewOnOriginalSite##About the authors
Tatyana B. Kruglova
Helmholtz National Medical Research Center of Eye Diseases
Email: krugtb@yandex.ru
ORCID iD: 0000-0001-8801-8368
SPIN-code: 5466-6754
MD, Dr. Sci. (Medicine)
Russian Federation, MoscowNaira S. Egiyan
Helmholtz National Medical Research Center of Eye Diseases
Author for correspondence.
Email: nairadom@mail.ru
ORCID iD: 0000-0001-9906-4706
SPIN-code: 4765-4725
MD, Cand. Sci. (Medicine)
Russian Federation, MoscowReferences
- Neroyev VV. Eye care management in Russian Federation. Russian Annals of Ophthalmology. 2014;130(6):8-12. EDN: THPQQB
- Kruglova TB, Katargina LA, Egiyan NS, Arestova NN. Surgical tactics and features of intraocular correction in children with congenital cataracts in the first year of life. Ophthalmosurgery. 2018;1:13–18. EDN: YVQVZN
- Kruglova TB, Katargina LA, Egiyan NS, et al. Remote functional results after congenital cataract extraction with intraocular lens implantation in children of the first year of life. Bulletin of ophthalmology. 2020;136(6):142–146. doi: 10.17116/oftalma202013606142
- Self JE, Taylor R, Solebo AL, et al. Cataract management in children: a review of the literature and current practice across five large UK centres. Eye (Lond). 2020;34(12):2197–2218. doi: 10.1038/s41433-020-1115-6
- Sand MK, Cholidis S, Rimstad K, et al. Long-term outcome of primary intraocular lens implantation in bilateral congenital cataract in infants with a median age of 35 days at surgery: a case series. BMJ Open Ophthalmol. 2021;6(1):e000836. doi: 10.1136/bmjophth-2021-000836
- Trivedi RH, Barnwell E, Wolf B, Wilson ME. A Model to predict postoperative axial length in children undergoing bilateral cataract surgery with primary intraocular lens implantation. Am J Ophthalmol. 2019;206:228–234. doi: 10.1016/j.ajo.2019.04.018
- Sudovskaya TV. Syndrome of primary persistent hyperplastic vitreous body in children: features of diagnosis, clinical presentation and surgical treatment. Russian Ophthalmological Journal. 2010;1:29–36. EDN: QCLJDX
- Katargina LA, Kruglova TB, Kononov LB, Egiyan NS. Extraction of congenital cataracts with IOL implantation in complicated forms of the lens. Practical Medicine. Ophthalmology. 2020;4(2):28–30. EDN: PCHGAJ
- Kuznetsova YD, Astasheva IB, Khatsenko IE, Zvereva AN. Tactics of management and surgical treatment of the posterior form of grade III and IV primary persistent hyperplastic vitreous syndrome in children. Modern technologies in ophthalmology. 2022;(1(41)):344–349. doi: 10.25276/2312-4911-2022-1-344-349
- Tereshchenko AV, Bely YA, Trifanenkova IG, Demyanchenko SK. Features of the clinical picture and surgery of congenital cataract in combination with primary persistent hyperplastic vitreous syndrome. Cataract and refractive surgery. 2013;13(2):10–14. EDN: RCTXCB
- Grenga R, Komaiha C, Bianchi G, et al. Persistenza del Vitreo Primitivo Iperplastico: presentazione di un caso clinico e breve revisione della letteratura [Persistent hyperplastic primary vitreous: case report and literature review]. Clin Ter. 2013;164(6):e497–503. Italian. doi: 10.7417/CT.2013.1644
Supplementary files
