CEREBRAL INTRAVENTRICULAR HEMORRHAGES AS A HIGH RISK FACTOR OF RETINOPATHY OF PREMATURITY DEVELOPMENT IN NEWBORNS WITH EXTREMELY LOW MASS OF A BODY AT BIRTH

The results of examination of 64 newborns with a mass of a body at birth from 670 to 990 g and gestation term from 24 to 30 weeks that stayed for treatment at the neonatal center of the Municipal Pediatric Clinic ь1 of Saint-Petersburg during 2008 are presented in the article. Among them 13 infants with severe cerebral intraventricular hemorrhage complicated by obstructive hydrocephalus made the main group of follow-up and the control group consisted of 51 infants without neonatal cerebral intraventricular hemorrhage. Comparative analysis of frequency and severity of retinopathy of prematurity manifestations in these groups was performed. The number of infants with retinopathy of prematurity in both groups was the same, at that the disease progressing up to the III stage including the threshold stage demanding preventive treatment was observed 5 times more often (P < 0.05) in infants with cerebral intraventricular hemorrhage in comparison with the control group. The number of unfavourable outcomes characterized by the retinal detachment and loss of vision among infants with severe forms of cerebral intraventricular hemorrhage made 20% that 4 times exceeded this index in the control group (5.1%). Severe forms of cerebral intraventricular hemorrhage, particularly those complicated by the progressing post-hemorrhage obstructive hydrocephalus, should be considered at the neonatal age to be a correctable high risk factor of unfavourable course of retinopathy of prematurity.

infants with extremely low mass of a body, retinopathy of prematurity, cerebral intraventricular hemorrhage