Hemangioma treatment efficiency of the combined orbital and periorbital areas in infants

This research was designed to evaluate the efficiency and safety of the orbital and periorbital areas hemangiomas’ combined conservative treatment in 105 infants. Hormone and radiotherapy used in 37 children, 33 children received only radiotherapy, 35 children underwent surgical intervention. The average age was 17,5±6,8 months. Radiotherapy was performed fractionally, single doses varied from 0.3 Gy to 1.7 Gy. Total number of fractions depended on tumor size and its rate of growth, nearly 5-8 per course, total tumor dose ranged from 8 to 12 Gy. It was demonstrated that previous surgical and parasurgical intervention lead to radiotherapy poor starting conditions, treatment prolongation, increase total radiation dose. This study shows a high clinical efficiency of hemangiomas’ combined treatment using radio- and hormonal therapy, good cosmetic effect and reducing of complications incidence. The use of these approaches in hemangiomas’ treatment is characterized by more rapid process completing, which is obviously due to the high radiosensitivity of infantshemangiomas.

hemangioma, children, orbital area, radiotherapy, hormone therapy