Email this article Planning clinical research. Question #2: Choosing of endpoints
- Authors: Tikhova G.P.1
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Affiliations:
- FSBI “Karelian Research Center of Russian Academy of Science"
- Issue: Vol 8, No 4 (2014)
- Pages: 67-70
- Section: Articles
- URL: https://journal-vniispk.ru/1993-6508/article/view/36260
- DOI: https://doi.org/10.17816/ра.v8i4.36260
- ID: 36260
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Abstract
The paper is devoted to the questions of correct choosing of endpoints that correspond the goal of the study as well as estimating of potential inaccuracy and bias of sample data due to particularities of different kind of endpoints. The author presents endpoints classification and considers various techniques to solve the problems arising from the endpoint nature.
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##article.viewOnOriginalSite##About the authors
Galina P. Tikhova
FSBI “Karelian Research Center of Russian Academy of Science"
Email: gala@critical.ru
185910, Petrozavodsk
References
- Adams-Huet B., Ahn C. Bridging clinical investigators and statisticians: writing the statistical methodology for a research proposal. J Investig Med. 2009; 57(8): 818-824.
- Prentice R.L. Surrogate endpoints in clinical trials: definition and operational criteria. Stat Med. 1989; 8(4): 431-440.
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