Cognitive impairment in patients with acute lacunar stroke
- 作者: Maksimova M.Y.1
-
隶属关系:
- Scientific Center for Neurology
- 期: 卷 31, 编号 9 (2024)
- 页面: 92-95
- 栏目: Neurology
- URL: https://journal-vniispk.ru/2073-4034/article/view/294172
- DOI: https://doi.org/10.18565/pharmateca.2024.9.92-95
- ID: 294172
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详细
Background. With increasing life expectancy in the population, vascular cognitive impairment (CI) is becoming one of the most important health problems.
Objective. Evaluation of the effectiveness of meldonium in patients with mild CI after lacunar stroke.
Methods. The open comparative study included 38 patients aged 45 to 55 years with mild CI diagnosed in the acute period of lacunar stroke. Diagnosis of mild CI was carried out on the basis of clinical and psychological examinations using the Arnold-Kohlman test in three parameters: abstract thinking, practical thinking, memory. Nineteen patients (the main group) were prescribed meldonium at a dose of 1000 mg intravenously for 20 days against the background of basic therapy, 19 patients (the comparison group) received basic therapy.
Results. Assessment of cognitive functions using the Arnold-Kohlman test revealed a statistically significant improvement in the performance of subtests for abstract thinking and memory in patients receiving meldonium.
Conclusion. The results of the treatment showed that the use of meldonium in patients with mild CI in the acute period of lacunar stroke is effective.
作者简介
M. Maksimova
Scientific Center for Neurology
编辑信件的主要联系方式.
Email: ncnmaximova@mail.ru
ORCID iD: 0000-0002-7682-6672
SPIN 代码: 5389-7907
Scopus 作者 ID: 7003900736
Researcher ID: C-7408-2012
Dr. Sci. (Med.), Professor, Head of the 2nd Neurological Department
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