Gender-related patterns of comorbidity in patients with chronic heart failure
- Authors: Sazhina A.S.1, Kurochkina O.N.2
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Affiliations:
- Clinical Cardiology Dispensary, Syktyvkar
- Pitirim Sorokin Syktyvkar State University
- Issue: Vol 32, No 8 (2025)
- Pages: 142-146
- Section: Articles
- URL: https://journal-vniispk.ru/2073-4034/article/view/365712
- DOI: https://doi.org/10.18565/pharmateca.2025.8.142-146
- ID: 365712
Cite item
Abstract
Background: The growing number of patients with chronic heart failure (CHF) attracts cardiologists worldwide. Comorbidity has a negative impact on outcomes in patients with CHF. Currently, there is a lack of research examining gender-related patterns of CHF progression in patients with comorbidity.
Objective: Evaluation of the gender-related patterns of comorbidity in patients with CHF.
Materials and methods: The study included 375 patients with CHF with low and moderately reduced ejection fraction based on echocardiography (EchoCG). Patients were divided into two groups: men and women. Comorbid pathology was studied, and the Charleston Comorbidity Index (CCI) was calculated. Statistical analysis was performed using Excel and Biostat, with Student’s t-test and Chi-square tests.
Results: In the study group of patients with CHF, the mean age was 64±11.9 years, and the proportion of men was 71.8%. The mean ejection fraction (EF) according to echocardiography was 33.4±9.8%, higher in women (35.5±8.9%) than in men (32.5±10.02%) (p=0.007). The most common comorbidities were arterial hypertension (AH) and type 2 diabetes mellitus (DM2). Women were more often diagnosed with chronic kidney disease (CKD) and anemia, while men were more often diagnosed with lung disease and severe liver disease. In the overall group, the CCI was 6.5±2.18 points, in women – 7.4±2.17 points, and in men – 6.14±2.07.
Conclusion: Timely consideration of identified gender-specific comorbidities can contribute to improved medical care for patients with CHF.
About the authors
A. S. Sazhina
Clinical Cardiology Dispensary, Syktyvkar
Author for correspondence.
Email: a.s.sazhina@gmail.com
ORCID iD: 0000-0002-0741-9053
Cardiologist, Department of Emergency Cardiology-2
Russian Federation, SyktyvkarO. N. Kurochkina
Pitirim Sorokin Syktyvkar State University
Email: olga_kgma@mail.ru
ORCID iD: 0000-0003-1595-7692
Dr. Sci. (Med.), Associate Professor, Professor of the Department of Therapy of the Medical Institute
Russian Federation, SyktyvkarReferences
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