Post-COVID syndrome in children and adolescents of a large industrial city
- Authors: Vavilova V.P.1, Vavilov A.M.1, Anisimova A.V.2, Lyachina N.V.3, Perevoshchikova N.K.1, Sosnina Y.G.3, Vavilov V.A.3, Bogomolova A.A.3, Filimonova I.V.3, Dobryak T.A.1, Vakulova T.M.1, Seliverstov I.A.1, Kabanova K.V.3, Ermolyuk I.A.3, Titorenko Y.S.4, Krekova N.P.4, Chernikh N.S.1, Drakina S.A.1
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Affiliations:
- Kemerovo State Medical University
- Kemerovo City Children's Clinical Hospital №2
- Atamanov Kuzbass Regional Children's Clinical Hospital
- Podgorbunsky Kuzbass Clinical Hospital for Emergency Medical Care
- Issue: Vol 25, No 8 (2023): Детские болезни
- Pages: 518-523
- Section: Articles
- URL: https://journal-vniispk.ru/2075-1753/article/view/161328
- DOI: https://doi.org/10.26442/26586630.2023.8.202324
- ID: 161328
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Abstract
Background. About 30 to 80% of children who have had a new coronavirus infection, suffer from post-COVID syndrome, the manifestations of which are diverse and persist for 12 weeks or more. Post-COVID syndrome remains an urgent problem in pediatrics, the clinical variants of which are diverse. There is no statistically significant relationship between the severity of coronavirus infection and the development of post-COVID syndrome. According to current data, the risk group for post-COVID syndrome includes children under 1 year of age, children with comorbid pathology.
Aim. To evaluate the frequency of development, clinical variants and course of post-COVID syndrome in children and teenager of a large industrial city in order to optimize recommendations for their rehabilitation after a new coronavirus infection.
Materials and methods. The were analyzed developmental histories of 6252 children and adolescents in Kemerovo (form 112/y) who had a new coronavirus infection.
Results. Data on post-COVID syndrome were recorded in the developmental histories of 3066 (49.04%) children and adolescents, analyzed by medical documents. At the age of 13–15 years, the incidence of post-COVID syndrome is 55%, which is statistically significantly higher than in other age groups (p=0.005–0.0001). The following clinical variants of post-COVID syndrome were identified: asthenic, respiratory, cardiac, recurrent ears, nose, and throat, functional gastrointestinal disorders and mixed, the frequency of which varies depending on age and gender. Children with comorbid pathology (iron deficiency anemia and grade I–II pharyngeal tonsil hypertrophy) are statistically significantly more likely to suffer from post-COVID syndrome (p=0.000000001; 0.00000009; 0.00000009) than children without a history of comorbid pathology.
Conclusion. Post-COVID syndrome occurs in half of children and adolescents who have had a new coronavirus infection. The frequency of post-COVID syndrome variants in children and adolescents differs. The presence comorbid pathology (iron deficiency anemia, pharyngeal tonsil hyperplasia of the 2 degree) increases the risk of developing post-COVID syndrome. It is necessary to examine patients in a timely manner for the purpose of differential diagnosis and drawing up an individual rehabilitation plan. Special attention should be paid to children with comorbid pathology.
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##article.viewOnOriginalSite##About the authors
Vera P. Vavilova
Kemerovo State Medical University
Author for correspondence.
Email: vavilovavp@mail.ru
ORCID iD: 0000-0001-8056-7274
D. Sci. (Med.)
Russian Federation, KemerovoAlexander M. Vavilov
Kemerovo State Medical University
Email: vavilovalexandr@mail.ru
ORCID iD: 0000-0003-2969-0669
D. Sci. (Med.)
Russian Federation, KemerovoAnna V. Anisimova
Kemerovo City Children's Clinical Hospital №2
Email: ane-cka@mail.ru
Cand. Sci. (Med.)
Russian Federation, KemerovoNatalia V. Lyachina
Atamanov Kuzbass Regional Children's Clinical Hospital
Email: natali_vic_l@mail.ru
Chief Doctor
Russian Federation, KemerovoNina K. Perevoshchikova
Kemerovo State Medical University
Email: nkp42@mail.ru
ORCID iD: 0000-0003-4844-2898
D. Sci. (Med.), Prof.
Russian Federation, KemerovoYulia G. Sosnina
Atamanov Kuzbass Regional Children's Clinical Hospital
Email: sosnina.bona@yandex.ru
Deputy Chief Doctor
Russian Federation, KemerovoVitaliy A. Vavilov
Atamanov Kuzbass Regional Children's Clinical Hospital
Email: Vavilov_va@mail.ru
ORCID iD: 0000-0002-2022-9246
Department Head
Russian Federation, KemerovoAnzhelika A. Bogomolova
Atamanov Kuzbass Regional Children's Clinical Hospital
Email: pesyak.anzhelika@mail.ru
Department Head
Russian Federation, KemerovoIrina V. Filimonova
Atamanov Kuzbass Regional Children's Clinical Hospital
Email: fiv21@rambler.ru
Pediatrician
Russian Federation, KemerovoTatyana A. Dobryak
Kemerovo State Medical University
Email: DDA_90@mail.ru
Cand. Sci. (Med.)
Russian Federation, KemerovoTamara M. Vakulova
Kemerovo State Medical University
Email: tamarahvakulova@yandex.ru
Аssistant
Russian Federation, KemerovoIlya A. Seliverstov
Kemerovo State Medical University
Email: ilia_seliverstov92@mail.ru
ORCID iD: 0000-0002-3969-894X
Аssistant
Russian Federation, KemerovoKristina V. Kabanova
Atamanov Kuzbass Regional Children's Clinical Hospital
Email: kristinakur94@mail.ru
Pediatrician
Russian Federation, KemerovoIgor A. Ermolyuk
Atamanov Kuzbass Regional Children's Clinical Hospital
Email: igor.ermoluk@mail.ru
Department Head
Russian Federation, KemerovoYevgeniya S. Titorenko
Podgorbunsky Kuzbass Clinical Hospital for Emergency Medical Care
Email: etitorenko1986@mail.ru
Department Head
Russian Federation, KemerovoNatalia P. Krekova
Podgorbunsky Kuzbass Clinical Hospital for Emergency Medical Care
Email: dpgkb2@mail.ru
Pediatrician
Russian Federation, KemerovoNatalia S. Chernikh
Kemerovo State Medical University
Email: nastep@mail.ru
ORCID iD: 0000-0001-5164-7494
Cand. Sci. (Med.)
Russian Federation, KemerovoSvetlana A. Drakina
Kemerovo State Medical University
Email: sdrakina@yandex.ru
ORCID iD: 0000-0001-7680-6578
Cand. Sci. (Med.)
Russian Federation, KemerovoReferences
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