Clinical case of mechanical and non-mechanical rhabdomyolysis complicated by acute kidney injury. Case report
- Authors: Ievlev E.N.1, Bekhtereva D.R.1, Khuzina Z.R.1, Chalgubaev E.K.2, Chekmareva I.N.2
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Affiliations:
- Izhevsk State Medical Academy
- City Clinical Hospital №6
- Issue: Vol 26, No 1 (2024): Cardiology and Nephrology
- Pages: 45-47
- Section: Articles
- URL: https://journal-vniispk.ru/2075-1753/article/view/256822
- DOI: https://doi.org/10.26442/20751753.2024.1.202634
- ID: 256822
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Abstract
To date, the problem of rhabdomyolysis remains relevant in Russia. Despite the introduction of modern methods of diagnosis, prevention and treatment, mortality remains high, up to 40%, especially with the addition of acute kidney injury. This article presents a clinical case of rhabdomyolysis, which arose as a result of the combined effects of non-traumatic (toxic effects of methadone, alcohol) and traumatic (vibration and non-physiological position during sleep) factors. This syndrome eventually led to the development of acute kidney damage up to anuria. In this clinical case, intensive infusion and detoxification therapy, including hemodialysis procedures, was carried out, which led to an almost complete restoration of the functional state of the kidneys. Thus, early diagnosis of rhabdomyolysis and AKI based on anamnesis, timely laboratory and instrumental diagnosis can prevent severe kidney damage up to terminal uremia and fatal consequences.
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##article.viewOnOriginalSite##About the authors
Evgeniy N. Ievlev
Izhevsk State Medical Academy
Email: inloja@mail.ru
ORCID iD: 0000-0002-0395-7946
Cand. Sci. (Med.)
Russian Federation, IzhevskDaria R. Bekhtereva
Izhevsk State Medical Academy
Email: behtereva2508@gmail.com
ORCID iD: 0009-0005-4208-9212
Student
Russian Federation, IzhevskZukhra R. Khuzina
Izhevsk State Medical Academy
Author for correspondence.
Email: zuhra-huzina@mail.ru
ORCID iD: 0009-0008-7274-5235
Student
Russian Federation, IzhevskEdgar K. Chalgubaev
City Clinical Hospital №6
Email: edgar_chalgubaev@mail.ru
ORCID iD: 0009-0006-3386-2303
Department Head
Russian Federation, IzhevskIrina N. Chekmareva
City Clinical Hospital №6
Email: perfect.solomina@mail.ru
ORCID iD: 0009-0006-4367-4752
Nephrologist
Russian Federation, IzhevskReferences
- Młynarska E, Krzemińska J, Wronka M, et al. Rhabdomyolysis-Induced AKI (RIAKI) Including the Role of COVID-19. Int J Mol Sci. 2022;23(15):8215. doi: 10.3390/ijms23158215
- Boudhabhay I, Poillerat V, Grunenwald A, et al. Complement activation is a crucial driver of acute kidney injury in rhabdomyolysis. Kidney Int. 2021;99(3):581-97. doi: 10.1016/j.kint.2020.09.033
- Saverymuthu A, Teo R, Zain JM, et al. Acute kidney injury following rhabdomyolysis in critically ill patients. J Crit Care Med. 2021;7(4):267-71. doi: 10.2478/jccm-2021-0025
- Stahl K, Rastelli E, Schoser B. A systematic review on the definition of rhabdomyolysis. J Neurol. 2020;267(4):877-82. doi: 10.1007/s00415-019-09185-4
- Bosch X, Poch E, Grau JM. Rhabdomyolysis and acute kidney injury. New Engl J Med. 2009;361(1):62-72. doi: 10.1056/NEJMra0801327
- Petejova N, Martinek A. Acute kidney injury due to rhabdomyolysis and renal replacement therapy: a critical review. Crit Care. 2014;18(3):224. doi: 10.1186/cc13897
- Kwiatkowska M, Chomicka I, Malyszko J. Rhabdomyoisis – induced acute kidney injury – an underestimated problem. Wiadomosci lekarskie. 2020;73(11):2543-8.
- Weidhase L, Haussig E, Haussig S, et al. Middle molecule clearance with high cut-off dialyzer versus high-flux dialyzer using continuous veno-venous hemodialysis with regional citrate anticoagulation: a prospective randomized controlled trial. PloS One. 2019;14(4):0215823. doi: 10.1371/journal.pone.0215823
- Есназарова Г.С., Омарова Х.С., Шамшидинова М.А., и др. Клинический случай рабдомиолиза. Medicine (Almaty). 2016;2(164):55-7 [Esnazarova GS, Omarova HS, Shamshidinova MA, et al. Clinical case of rhabdomyolysis. Medicine (Almaty). 2016;2(164):55-7 (in Russian)].
- Иськова И.А., Кляритская И.Л., Цапяк Т.А., и др. Статин-индуцированная миопатия. Крымский терапевтический журнал. 2021;3:64-70 [Iskova IA, Klaritskaya IL, Tsapyak TA, et al. Statin-induced myopathy. Crimean Journal of Internal Diseases. 2021;3:64-70 (in Russian)].
- Кузнецов О.А., Лодягин А.Н., Батоцыренов Б.В., и др. Особенности клинического течения острых отравлений метадоном, осложненных развитием синдрома позиционного сдавления и системного рабдомиолиза. Токсикологический вестник. 2015;4(133):38-43 [Kuznetsov OA, Lodyagin AN, Batotsyrenov BV, et al. Features of the clinical course of acute methadone poisoning complicated by the development of positional compression syndrome and systemic rhabdomyolysis. Toxicological Review. 2015;4(133):38-43 (in Russian)].
- Бердников Г.А., Кудряшова Н.Е., Мигунова Е.В., и др. Развитие рабдомиолиза в отдаленном периоде перенесенной новой коронавирусной инфекции COVID-19 (клиническое наблюдение). Журнал им. Н.В. Склифосовского «Неотложная медицинская помощь». 2021;10(3):452-9 [Berdnikov GA, Kudryashova NE, Migunova EV, et al. Development of rhabdomyolysis in the long-term period of Previous new coronavirus infection COVID-19 (Clinical case report). Russian Sklifosovsky Journal "Emergency Medical Care". 2021;10(3):452-9 (in Russian)]. doi: 10.23934/2223-9022-2021-10-3-452-459
- Борисов А.Г., Чернов С.А., Потехин Н.П., Романов В.П. Нетравматический рабдомиолиз как причина острого повреждения почек. Нефрология. 2019;23(приложение 1):44-5 [Borisov AG, Chernov SA, Potekhin NP, Romanov VP. Nontraumatic rhabdomyolysis as the reason of acute renal injury. Nephrology. 2019;23((Suppl. 1):44-5 (in Russian)]. doi: 10.36485/1561-6274-2019-23-5-44-54
- Ghasemi S, Izadpanahi S, Yaghoubi MA, et al. Methadone associated long term hearing loss and nephrotoxicity; a case report and literature review. Subst Abuse Treat Prev Policy. 2019;14(1):48. doi: 10.1186/s13011-019-0236-z
- Alinejad S, Ghaemi K, Abdollahi M, Mehrpour O. Nephrotoxicity of methadone: a systematic review. Springerplus. 2016;5(1):2087. doi: 10.1186/s40064-016-3757-1
- Волков Е.В., Гуров А.Ю., Фишер В.В., Батчаева Л.Х. Случай оказания медицинской помощи пациенту с нетипичным дебютом синдрома травматического рабдомиолиза. Сибирское медицинское обозрение. 2020;2(122):98-102 [Volkov EV, Gurov AY, Fischer VV, Batchaeva LH. Сase of providing medical care to a patient with atypical onset of traumatic rhabdomyolysis syndrome. Siberian Medical Review. 2020;2(122):98-102 (in Russian)]. doi: 10.20333/2500136-2020-2-98-102
- Донской Д.Н. Рабдомиолиз, как причина острого повреждения почек в детском возрасте. Инновационная наука. 2021;7:148-9 [Donskoy DN. Rhabdomyolysis as a cause of acute kidney injury in childhood. Innovation Science. 2021;7:148-9 (in Russian)].
- Ould-Nana I, Cillis M, Gizzi M, et al. Rhabdomyolysis and acute kidney injury induced by the association of rosuvastatin and abiraterone: A case report and review of the literature. J Oncol Pharm Pract. 2021;27(1):216-9. doi: 10.1177/1078155220923001
- Федорова А.А., Кутепов Д.Е., Зубарев А.В., и др. Рабдомиолиз: что нового в диагностике и лечении? Кремлевская медицина. Клинический вестник. 2020;2:102-9 [Fedorova AA, Kutepov DE, Zubarev AV, et al. Rhabdomyolysis: What's new in diagnostics and treatment? Kremlin Medicine Journal. 2020;2:102-9 (in Russian)]. doi: 10.26269/4n94-0746
- Sawhney JS, Kasotakis G, Goldenberg A, et al. Management of rhabdomyolysis: A practice management guideline from the Eastern Association for the Surgery of Trauma. Am J Surg. 2022;224(1 Pt A):196-204. doi: 10.1016/j.amjsurg.2021.11.022
- Hui WF, Hon KL, Lun KS, et al. Successful treatment of rhabdomyolysis-associated acute kidney injury with haemoadsorption and continuous renal replacement therapy. Case Rep Pediatr. 2021;2021:2148024. doi: 10.1155/2021/2148024
- Long B, Koyfman A, Gottlieb M. An evidence-based narrative review of the emergency department evaluation and management of rhabdomyolysis. Am J Emerg Med. 2019;37(3):518-23. doi: 10.1016/j.ajem.2018.12.061
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