An unusual case of respiratory failure in a patient with Randu–Osler–Weber disease. Case report

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Abstract

Clinical observation is of interest due to the shift in the vector of the main complaints of the classic manifestation of Randu–Osler–Weber disease in the form of epistaxis and anemia syndrome towards the syndrome of severe respiratory failure, the cause of which is the presence of arteriovenous malformations in the lungs. The importance of an interdisciplinary approach to the diagnosis and treatment of patients with Randu–Osler–Weber disease is discussed.

About the authors

Valery I. Podzolkov

Sechenov First Moscow State Medical University (Sechenov University)

Email: pokrovskaya_a_e@staff.sechenov.ru
ORCID iD: 0000-0002-0758-5609

D. Sci. (Med.), Prof.

Russian Federation, Moscow

Anna E. Pokrovskaya

Sechenov First Moscow State Medical University (Sechenov University)

Author for correspondence.
Email: pokrovskaya_a_e@staff.sechenov.ru
ORCID iD: 0000-0002-8875-9032

Cand. Sci. (Med.)

Russian Federation, Moscow

Victoria S. Ivanova

Sechenov First Moscow State Medical University (Sechenov University)

Email: pokrovskaya_a_e@staff.sechenov.ru
ORCID iD: 0009-0005-3548-357X

Clinical Resident

Russian Federation, Moscow

Kseniya E. Krylova

Sechenov First Moscow State Medical University (Sechenov University)

Email: pokrovskaya_a_e@staff.sechenov.ru
ORCID iD: 0009-0009-2485-9008

Clinical Resident

Russian Federation, Moscow

Polina V. Luchkina

Sechenov First Moscow State Medical University (Sechenov University)

Email: pokrovskaya_a_e@staff.sechenov.ru
ORCID iD: 0009-0000-8260-2491

Student

Russian Federation, Moscow

Fatima E. Murzakhanova

Sechenov First Moscow State Medical University (Sechenov University)

Email: pokrovskaya_a_e@staff.sechenov.ru
ORCID iD: 0009-0004-2388-3384

Student

Russian Federation, Moscow

Darya D. Gerasimova

Sechenov First Moscow State Medical University (Sechenov University)

Email: pokrovskaya_a_e@staff.sechenov.ru
ORCID iD: 0009-0004-7015-0829

Student

Russian Federation, Moscow

Ivan D. Medvedev

Sechenov First Moscow State Medical University (Sechenov University)

Email: pokrovskaya_a_e@staff.sechenov.ru
ORCID iD: 0000-0003-4210-2841

Cand. Sci. (Med.)

Russian Federation, Moscow

References

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Supplementary files

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1. JATS XML
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2. Fig. 1. The patient's appearance: signs of severe acrocyanosis, fingers in the form of "drumsticks" and nails in the form of "watch glasses", telangiectasia on the fingers and tongue.

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3. Fig. 2. Spirography of the patient.

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4. Fig. 3. CT scan of the OGK patient.

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5. Fig. 4. SPECT of the patient's lungs.

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