Challenges in the diagnosis of adult-onset Still's disease. Clinical case
- Authors: Pokrovskaya A.E.1, Abramov V.V.1, Podzolkov V.I.1
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Affiliations:
- Sechenov First Moscow State Medical University (Sechenov University)
- Issue: Vol 27, No 9 (2025): Otorhinolaryngology and pulmonology
- Pages: 508-511
- Section: Articles
- URL: https://journal-vniispk.ru/2075-1753/article/view/356624
- DOI: https://doi.org/10.26442/20751753.2025.9.203460
- ID: 356624
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Abstract
A clinical case illustrates the challenges of verifying adult-onset Still's disease, a rare autoinflammatory disease with no pathognomonic symptoms and no specific laboratory markers. A 50-year-old female patient with fever lasting more than 2 weeks, arthralgia, and exanthema was diagnosed with adult Still's disease after excluding infectious, oncological, and autoimmune causes of fever of unknown origin. Administration of an adequate dose of systemic glucocorticosteroids resulted in symptom relief within the first day. A specific feature of the clinical case was the late onset of the disease. This case highlights the need for a multidisciplinary approach in the diagnosis of adult-onset Still's disease.
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##article.viewOnOriginalSite##About the authors
Anna E. Pokrovskaya
Sechenov First Moscow State Medical University (Sechenov University)
Author for correspondence.
Email: pokrovskaya_a_e@staff.sechenov.ru
ORCID iD: 0000-0002-8875-9032
Cand. Sci. (Med.)
Russian Federation, MoscowVadim V. Abramov
Sechenov First Moscow State Medical University (Sechenov University)
Email: pokrovskaya_a_e@staff.sechenov.ru
ORCID iD: 0009-0006-8151-8865
Clinical Resident
Russian Federation, MoscowValery I. Podzolkov
Sechenov First Moscow State Medical University (Sechenov University)
Email: pokrovskaya_a_e@staff.sechenov.ru
ORCID iD: 0000-0002-0758-5609
D. Sci. (Med.), Prof.
Russian Federation, MoscowReferences
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