Tikagrelor kak novaya vozmozhnost' povysheniya effektivnosti lecheniya ostrogo koronarnogo sindroma: mesto v sovremennykh klinicheskikh rekomendatsiyakh
- Authors: Yavelov I.S1
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Affiliations:
- ГБОУ ВПО РНИМУ им. Н.И.Пирогова Минздравсоцразвития РФ, Москва
- Issue: Vol 14, No 1 (2012)
- Pages: 27-30
- Section: Articles
- URL: https://journal-vniispk.ru/2075-1753/article/view/93515
- ID: 93515
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Abstract
В конце 2011 г. в Российской Федерации был расширен список антиагрегантов, разрешенных к использованию при лечении острого коронарного синдрома (ОКС), инфаркта миокарда (ИМ) и нестабильной стенокардии за счет добавления к клопидогрелу двух новых ингибиторов рецептора тромбоцитов к аденозиндифосфату P2Y12 прасугрела и тикагрелора. Наиболее широким спектром показаний обладает тикагрелор. В этом сообщении представлены факты, ставшие основой для сложившихся представлений о роли этого лекарственного средства в лечении различных категорий больных с ОКС. Сведения об эффектах, ожидаемых при применении тикагрелора у больных с ОКС, получены в исследовании PLATO, в котором сочетание ацетилсалициловой кислоты (АСК) и тикагрелора сопоставлено со стандартным сочетанием АСК и клопидогрела. Результаты этого крупного клинического исследования, публикуемые с 2009 г., стали основанием для одобрения тикагрелора регулирующими инстанциями и его включения в современные клинические рекомендации.
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##article.viewOnOriginalSite##About the authors
I. S Yavelov
ГБОУ ВПО РНИМУ им. Н.И.Пирогова Минздравсоцразвития РФ, МоскваКафедра клинической фармакологии
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