Adenomy gipofiza i sindrom mnozhestvennykh neoplaziy 1-go tipa


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Abstract

К синдромам множественных эндокринных неоплазий (МЭН) относится ряд редких наследственных заболеваний, характеризующихся опухолевым поражением нескольких эндокринных желез. Синдромы МЭН обусловлены мутациями в определенных генах, приводящими к характерным клиническим проявлениям. В основном принято выделять МЭН 1-го типа (МЭН-1) и МЭН 2-го типа (МЭН-2). Однако множественное опухолевое поражение эндокринных желез встречается и при других тяжелых наследственных состояниях: синдроме Гиппеля–Линдау (von Hippel – Lindau), синдроме семейной параганглиомы, синдроме Коудена (Cowden), комплексе Карни (Carney) и др.

About the authors

L. Ya Rozhinskaya

ФГБУ Эндокринологический научный центр Минздрава РФ, Москва

L. G Rostomyan

ФГБУ Эндокринологический научный центр Минздрава РФ, Москва

A. N Tyul'pakov

ФГБУ Эндокринологический научный центр Минздрава РФ, Москва

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