Features of pharmacological action and the use of dipyridamole for secondary prevention of ischemic stroke
- Authors: Tairova R.T1
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Affiliations:
- N.I.Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation
- Issue: Vol 19, No 2-3 (2017)
- Pages: 15-18
- Section: Articles
- URL: https://journal-vniispk.ru/2075-1753/article/view/94684
- ID: 94684
Cite item
Abstract
The review presents modern data from domestic and foreign studies on the efficacy and safety of dipyridamole for the prevention of ischemic stroke. It is shown that dipyridamole is an effective complex action drug with a good safety profile and the ability to have a positive combined antiplatelet and vascular action, which makes it very promising for the prevention of the repeated development of acute cerebrovascular accident. Modern clinical approaches and indications for mono-and combination therapy with antiplatelet agents in the secondary prevention of cerebral stroke are considered.
Full Text
##article.viewOnOriginalSite##About the authors
R. T Tairova
N.I.Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federationассистент каф. неврологии и медицинской генетики, ст. науч. сотр. НИИ цереброваскулярной патологии и инсульта 117997, Russian Federation, Moscow, ul. Ostrovitianova, d. 1
References
- Гусев Е.И., Коновалов А.Н., Скворцова В.И. Неврология и нейрохирургия. 4-е изд. Т. 1. М.: ГЭОТАР-Медиа, 2015, с. 335.
- Скворцова В.И., Чазова И.Е., Стаховская Л.В. Вторичная профилактика инсульта. М., 2002; с. 16-81
- Kapil N. et al: Antiplatelet and Anticoagulant Therapies for Prevention of Ischemic Stroke. Clin Appl Thromb Hemost 2017; 23 (4): 301-18. doi: 10.1177/1076029616660762.
- Стаховская Л.В., Квасова О.В., Пряникова Н.А. и др. Применение дипиридамола (курантила) для вторичной профилактики инсульта. Журн. неврологии и психиатрии им С.С.Корсакова. 2000; 4: 28-31
- Fisher M, Bogouslavsky J. JAMA 1998; 279: 1298-303.
- Скворцова В.И., Евзельман М.А. Ишемический инсульт. Орел, 2006; с. 233-43.
- Квасова О.В. Применение курантила и аспирина для вторичной профилактики ишемического инсульта. Дис. … канд. мед. наук. М., 2005.
- De Schryver E.L, Alga A, van Gijn. Dipiridamol: for Dipyridamole for preventing stroke and other vascular events in patients with vascular disease. Cochrane 2003; CD001820.
- ESPS-1 Group: The European Stroke Prevention Study. Lancet 1987; 2: 1351-4.
- ESPS-2 Group: The European Stroke Prevention Stude 2. J Neurol Sci 1997; 151: 1-77.
- Hirt L, Carrera E. Antiplatelet therapy in secondary stroke prevention. Rev Med Suisse 2017; 13 (560): 907-10.
- Sandercock P, Bamford J, Dennis M. et al. Br Med 1996; 335: 1001-9.
- Henrikson C. Atrial Fibrillation Investigation. Arch Int Med 1994; 154: 1449-57.
- Antiplatelet Triallists. Collaboration. BMJ 1988; 308: 81-106.
- Gijn J, Kapple L.J. et al. ESPIRIT Studu Group, Halkes PHA: Aspirin plus dipyridamole versus aspirin alone after cerebral ischaemia of arterial origin: randomized controlled trial. Lancet 2006; 367: 1665-73.
- Ross S.D, Alien I.E. Arch Int Med 1999; 159: 1793-802.
- Скворцова В.И., Стаховская Л.В., Пряникова Н.А. и др. Антиагреганты в профилактике ишемического инсульта: пути повышения эффективности. Справочник поликлинического врача. 2006; 2: 98-101.
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