Screening method for diagnosis of pharyngolaryngeal reflux

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Abstract

Pharyngolaryngeal reflux (PLR) can cause the upper respiratory tract pathology. To diagnose PLR based on complaints is rather difficult, due to the absence of typical manifestations of reflux syndrome in some cases of the disease. The use of daily impedance pH monitoring of the esophagus is not always possible due to the invasiveness and unavailability of the method. The aim of the study was to develop an affordable non-invasive method for diagnosing PLR. The study group consisted of 48 patients with PLR proven by the results of impedance pH-monitoring. The control group consisted of 20 healthy patients. The “Pharyngolaryngeal reflux index” questionnaire was developed based on the analysis of patient complaints. The questionnaire was assessed using ROC analysis. Patients who scored 5.5 points according to the results of the questionnaire with a probability of 93.2% have PLR. Thus, a method for the diagnosis of PLR has been developed, including the simultaneous comparison of the laryngoscopic signs of PLR with the highest diagnostic sensitivity (hyperemia, edema, maceration of the interarytenoid mucosa) and “Pharyngolaryngeal reflux index" questionnaire results, which allows diagnosing of PLR.

About the authors

Marina A. Ryabova

Pavlov First Saint Petersburg State Medical University

Email: marinaryabova@mail.ru
д-р мед. наук, проф. каф. Saint Petersburg, Russia

Natalia A. Shumilova

Pavlov First Saint Petersburg State Medical University

канд. мед. наук, ассистент каф. Saint Petersburg, Russia

Liubov V. Georgieva

Pavlov First Saint Petersburg State Medical University

Email: lubov_pestakova@mail.ru
аспирантка каф. Saint Petersburg, Russia

Artem V. Tishkov

Pavlov First Saint Petersburg State Medical University

зав. каф. физики Saint Petersburg, Russia

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