Eosinophilia as a predictor of recurrent course polypoid rhinosinusitis after surgical treatment

Introduction. Respiratory diseases, in particular polypoid rhinosinusitis and bronchial asthma, occupy one of the first places in the overall structure of morbidity. The recurrent course of polypoid rhinosinusitis determines the uncontrolled course of bronchial asthma in patients with combined pathology. Achieving the control of bronchial asthma and polypoid rhinosinusitis is the main goal of maintaining this category of patients. Aim. The objective of this study was to investigate the role of biological markers in predicting the early recurrence of polypoid rhinosinusitis after endoscopic polysinusotomy. Materials and methods. The study involved 73 patients diagnosed with polypoid rhinosinusitis and polypoid rhinosinusitis in combination with bronchial asthma. All patients underwent bilateral endoscopic polysinusotomy followed by dynamic observation during the year. The dynamics of blood eosinophilia and the number of nasal secretion eosinophils were evaluated. A morphological examination of the tissue of distant polyps was performed. Conclusions. It has been shown that the eosinophilic nature of polyps as well as a sustained increase in the number of blood eosinophils and nasal secretions are prognostically unfavorable factors for an early relapse of the polypoid rhinosinusitis.

polypoid rhinosinusitis, bronchial asthma, blood eosinophilia, respiratory diseases