DURATION OF POSTVACCINAL IMMUNITY AGAINST HEPATITIS B IN HEALTH CARE WORKERS IN ST. PETERSBURG
- Authors: Kalinina Z.P.1, Dar’ina M.G.1, Movchan K.N.1, Mamicheva O.Y.2, Gagarkina I.B.3, Averina T.Y.3, Balabash O.A.3, Yefimova L.I.3, Potemkina I.V.3
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Affiliations:
- 198095, Russian Federation, St. Petersburg, str. Shkapina, 30, letter A, St. Petersburg Мedical Informational-Analytical Center. North-Western State Medical University named after I.I. Mechnikov, St. Petersburg, Russian Federation
- North-Western State Medical University named after I.I. Mechnikov, St. Petersburg, Russian Federation
- 198095, Russian Federation, St. Petersburg, str. Shkapina, 30, letter A, St. Petersburg Мedical Informational-Analytical Center.
- Issue: Vol 5, No 1 (2015)
- Pages: 89-92
- Section: SHORT COMMUNICATIONS
- URL: https://journal-vniispk.ru/2220-7619/article/view/118275
- DOI: https://doi.org/10.15789/2220-7619-2015-1-
- ID: 118275
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Abstract
Immunization against hepatitis В is the most effective method of preventing this disease. Study of quantitative characteristics of postvaccinal immunity against viral hepatitis В in 214 health care workers from different institutions of St. Petersburg has shown that HBV vaccine provides a long term immunity in 80% of cases with the absence of manifest forms of the disease. The duration of circulation of high titers of antibodies depended on the age of people when vaccination was provided. The highest level of immunity was observed in people vaccinated before the age of 30 years (84,0–90,6%). Reduction of immunity level in vaccinated health care workers after 5 years from the date of vaccination requires revaccination against viral hepatitis B after pre-vaccination screening.
About the authors
Z. P. Kalinina
198095, Russian Federation, St. Petersburg, str. Shkapina, 30, letter A, St. Petersburg Мedical Informational-Analytical Center.North-Western State Medical University named after I.I. Mechnikov, St. Petersburg, Russian Federation
Author for correspondence.
Email: KalininaZ@miac.zdrav.spb.ru
PhD (Medicine), Epidemiologist of Sector for Clinical Epidemiology of the Organizational-Methodical Department
for Monitoring the Quality of Medical Practice St. Petersburg Мedical Informational Analytical Center; Associate Professor of the Department of Epidemiology, Parasitology and Dezinfektologii North-Western State medical University named after I.I. Mechnikov, St. Petersburg, Russian Federation;
M. G. Dar’ina
198095, Russian Federation, St. Petersburg, str. Shkapina, 30, letter A, St. Petersburg Мedical Informational-Analytical Center.North-Western State Medical University named after I.I. Mechnikov, St. Petersburg, Russian Federation
Email: fake@neicon.ru
PhD (Medicine), Head of the Epidemiologist Sector of Clinical Epidemiology of Organizational-Methodical Department for Monitoring the Quality of Medical Practice St. Petersburg Medical Informational Analytical Center; Assistant of Chair Epidemiology, Parasitology and Dezinfektologii North-Western State Medical University named after I.I. Mechnikov, St. Petersburg, Russian Federation;
K. N. Movchan
198095, Russian Federation, St. Petersburg, str. Shkapina, 30, letter A, St. Petersburg Мedical Informational-Analytical Center.North-Western State Medical University named after I.I. Mechnikov, St. Petersburg, Russian Federation
Email: fake@neicon.ru
PhD (Medicine), Head of the Organizational- Methodical Department for Monitoring the Quality of Medical Practice St. Petersburg Medical Informational Analytical Center; Professor of Chair Surgery named after N.D. Monastirskyi North- Western State Medical University named after I.I. Mechnikov,
St. Petersburg, Russian Federation;
O. Yu. Mamicheva
North-Western State Medical University named after I.I. Mechnikov, St. Petersburg, Russian Federation
Email: fake@neicon.ru
PhD Candidate North-Western State Medical University named after I.I. Mechnikov, St. Petersburg, Russian Federation;
I. B. Gagarkina
198095, Russian Federation, St. Petersburg, str. Shkapina, 30, letter A, St. Petersburg Мedical Informational-Analytical Center.
Email: fake@neicon.ru
Epidemiologist, Expert of St. Petersburg Medical Informational Analytical Center, St. Petersburg, Russian Federation;
T. Ya. Averina
198095, Russian Federation, St. Petersburg, str. Shkapina, 30, letter A, St. Petersburg Мedical Informational-Analytical Center.
Email: fake@neicon.ru
Epidemiologist, Expert of St. Petersburg Medical Informational Analytical Center, St. Petersburg, Russian Federation;
O. A. Balabash
198095, Russian Federation, St. Petersburg, str. Shkapina, 30, letter A, St. Petersburg Мedical Informational-Analytical Center.
Email: fake@neicon.ru
Epidemiologist, Expert of St. Petersburg Medical Informational Analytical Center, St. Petersburg, Russian Federation;
L. I. Yefimova
198095, Russian Federation, St. Petersburg, str. Shkapina, 30, letter A, St. Petersburg Мedical Informational-Analytical Center.
Email: fake@neicon.ru
Epidemiologist, Expert of St. Petersburg Medical Informational Analytical Center, St. Petersburg, Russian Federation;
I. V. Potemkina
198095, Russian Federation, St. Petersburg, str. Shkapina, 30, letter A, St. Petersburg Мedical Informational-Analytical Center.
Email: fake@neicon.ru
Epidemiologist, Expert of St. Petersburg Medical Informational Analytical Center, St. Petersburg, Russian Federation.
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