THE FEATURES OF BLOOD IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH VARIOUS FORMS OF BRUCELLOSIS
- 作者: Logvinenko O.V.1, Rakitinа C.L.1, Ponomarenko D.G.1, Kostychenko M.V.1, Sarkisian N.S.1, Berdnikova T.V.1
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隶属关系:
- The Federal Government Public Health Institution Stavropol Institute for Plague Control of the Rospotrebnadzor, Stavropol
- 期: 卷 3, 编号 3 (2013)
- 页面: 275-278
- 栏目: SHORT COMMUNICATIONS
- URL: https://journal-vniispk.ru/2220-7619/article/view/118387
- DOI: https://doi.org/10.15789/2220-7619-2013-3-275-278
- ID: 118387
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Abstract. Results of current study have shown that acute brucellosis is characterized by increase of T-helper and cytotoxic T-lymphocytes and decrease of phagocytic activity of neutrophyls in the blood. In patients with chronic form of disease the decline of T-helper and cytotoxic T-lymphocytes together with activation of humoral immunity and increasing of B-lymphocytes and levels of immunoglobulins A and G have been observed. Thus, revealed changes indicating the formation of secondary immunodeficiency in chronic disease course. Results of the study confirmed the needs for a permanent immunological monitoring of patients with brucellosis as well as conducting a comprehensive immunological testing of patients to develop the individual scheme of corrective therapy.
作者简介
O. Logvinenko
The Federal Government Public Health Institution Stavropol Institute for Plague Control of the Rospotrebnadzor, Stavropol
编辑信件的主要联系方式.
Email: patomorf@yandex.ru
PhD (Biology), Leading Research Associate, Laboratory of Phatomorfology Especially Dangerous Contagions
355035, Russian Federation, Stavropol, Sovetskaia str., 13–15俄罗斯联邦
C. Rakitinа
The Federal Government Public Health Institution Stavropol Institute for Plague Control of the Rospotrebnadzor, Stavropol
Email: patomorf@yandex.ru
PhD (Medicine), Leading Research Associate, Laboratory of Phatomorfology Especially Dangerous Contagions 俄罗斯联邦
D. Ponomarenko
The Federal Government Public Health Institution Stavropol Institute for Plague Control of the Rospotrebnadzor, Stavropol
Email: patomorf@yandex.ru
PhD (Biology), Chief, Laboratory of Phatomorfology Especially Dangerous Contagions 俄罗斯联邦
M. Kostychenko
The Federal Government Public Health Institution Stavropol Institute for Plague Control of the Rospotrebnadzor, Stavropol
Email: patomorf@yandex.ru
Research Associate, Laboratory of Phatomorfology Especially Dangerous Contagions 俄罗斯联邦
N. Sarkisian
The Federal Government Public Health Institution Stavropol Institute for Plague Control of the Rospotrebnadzor, Stavropol
Email: patomorf@yandex.ru
Junior Research Associate, Laboratory of Phatomorfology Especially Dangerous Contagions 俄罗斯联邦
T. Berdnikova
The Federal Government Public Health Institution Stavropol Institute for Plague Control of the Rospotrebnadzor, Stavropol
Email: patomorf@yandex.ru
Junior Research Associate, Laboratory of Brucellosis 俄罗斯联邦
参考
- Безопасность работы с микроорганизмами I–II групп патогенности (опасности). Санитарно-эпидемиологические правила СП 1.3.1285–03 / Бюллетень нормативных и методических документов Госсанэпиднадзора. — Вып. 3 (13). — М.: 2003. — С. 67–144. Bezopasnost` raboty s mikroorganizmami I–II grupp patogennosti (opasnosti). Sanitarno-epidemiologicheskie pravila SP 1.3.1285-03 [Safe work with microorganisms of I–II groups of danger. The sanitary epidemiological rules SR 1.3.1285–03]. Byulleten` normativnykh i metodicheskikh dokumentov Gossanepidnadzora [The Bulletin of normative and methodological documents of Gossanepidnadzor]. Issue 3 (13), Moscow, 2003, pp. 67–144.
- Борисов Л.Б. Медицинская микробиология, вирусология и иммунология. — М.: МИА, 2005. — 423 с. Borisov L.B. Meditsinskaya mikrobiologiya, virusologiya i immunologiya [Medical microbiology, virology and immunology]. Moscow, MIA, 2005. 423 p.
- Вершилова П.А., Чернышева М.И., Князева Э.Н. Патогенез и иммунология бруцеллеза. — М.: Медицина, 1974. — 271 с. Vershilova P.A., Chernysheva M.I., Knyazeva E.N. Patogenez i immunologiya brutselleza [Pathogenesis and immunology of brucellosis]. Moscow, Meditsina, 1974. 271 p.
- Кишкун А.А. Руководство по лабораторным методам диагностики. — М.: «ГЕОТАР-Медиа», 2007. — 779 с. Kishkun A.A. Rukovodstvo po laboratornym metodam diagnostiki [The handbook on laboratory methods of diagnostics]. Moscow, GEOTAR-Media, 2007. 779 p.
- Лямкин Г.И., Тихенко Н.И., Русанова Д.В., Манин Е.А. Современная эпидемиологическая обстановка по бруцеллезу в Российской Федерации // Актуальные проблемы болезней, общих для человека и животных: материалы Всерос. науч-практ. конф. — Ставрополь: «Экспо-Медиа», 2012. — С. 51–52. Lyamkin G.I., Tikhenko N.I., Rusanova D.V., Manin E.A. Sovremennaya epidemiologicheskaya obstanovka po brutsellezu v Rossiyskoy Federatsii [The modern epidemiological situation on brucellosis in the Russian Federation]. Aktual`nye problemy bolezney, obshchikh dlya cheloveka i zhivotnykh: materialy Vseros. nauch-prakt. konf. [Actual problems of diseases common for human and animals: Proc. Russian conference]. Stavropol: Ekspo-Media, 2012, pp. 51–52.
- Методы клинических лабораторных исследований / Под ред. В.С. Камышникова. — 4-е изд. — М.: МЕДпресс-информ, 2011. — 752 с. Metody klinicheskikh laboratornykh issledovaniy (Pod red. V.S. Kamyshnikova) [The methods of clinical laboratory testing (Ed by V.S. Kamyshnikova)]. 4th edition. Moscow, MEDpress-inform, 2011. 752 p.
- Пономаренко Д.Г., Ракитина Е.Л., Логвиненко О.В., Голубь О.Г., Бердникова Т.В. Изменение иммунологических показателей у людей больных хроническим бруцеллезом // Неделя медицины Ставрополья — Здоровье населения и среда обитания: материалы 16-й ежегодной конф. — Ставрополь, 2012. — С. 180–184. Ponomarenko D.G., Rakitina E.L., Logvinenko O.V., Golub` O.G., Berdnikova T.V. Izmenenie immunologicheskikh pokazateley u lyudey bol`nykh khronicheskim brutsellezom [Changes of immunological indices in patients with chronic brucellosis]. Nedelya meditsiny Stavropol`ya — Zdorov`e naseleniya i sreda obitaniya: materialy 16-y ezhegodnoy konf. [Week of Stavropol medicine — Population health and environment: Proc. 16th annual conf.]. Stavropol, 2012, pp. 180–184.
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