THE FEATURES OF BLOOD IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH VARIOUS FORMS OF BRUCELLOSIS
- Authors: Logvinenko O.V.1, Rakitinа C.L.1, Ponomarenko D.G.1, Kostychenko M.V.1, Sarkisian N.S.1, Berdnikova T.V.1
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Affiliations:
- The Federal Government Public Health Institution Stavropol Institute for Plague Control of the Rospotrebnadzor, Stavropol
- Issue: Vol 3, No 3 (2013)
- Pages: 275-278
- Section: SHORT COMMUNICATIONS
- URL: https://journal-vniispk.ru/2220-7619/article/view/118387
- DOI: https://doi.org/10.15789/2220-7619-2013-3-275-278
- ID: 118387
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Abstract
Abstract. Results of current study have shown that acute brucellosis is characterized by increase of T-helper and cytotoxic T-lymphocytes and decrease of phagocytic activity of neutrophyls in the blood. In patients with chronic form of disease the decline of T-helper and cytotoxic T-lymphocytes together with activation of humoral immunity and increasing of B-lymphocytes and levels of immunoglobulins A and G have been observed. Thus, revealed changes indicating the formation of secondary immunodeficiency in chronic disease course. Results of the study confirmed the needs for a permanent immunological monitoring of patients with brucellosis as well as conducting a comprehensive immunological testing of patients to develop the individual scheme of corrective therapy.
About the authors
O. V. Logvinenko
The Federal Government Public Health Institution Stavropol Institute for Plague Control of the Rospotrebnadzor, Stavropol
Author for correspondence.
Email: patomorf@yandex.ru
PhD (Biology), Leading Research Associate, Laboratory of Phatomorfology Especially Dangerous Contagions
355035, Russian Federation, Stavropol, Sovetskaia str., 13–15Russian Federation
C. L. Rakitinа
The Federal Government Public Health Institution Stavropol Institute for Plague Control of the Rospotrebnadzor, Stavropol
Email: patomorf@yandex.ru
PhD (Medicine), Leading Research Associate, Laboratory of Phatomorfology Especially Dangerous Contagions Russian Federation
D. G. Ponomarenko
The Federal Government Public Health Institution Stavropol Institute for Plague Control of the Rospotrebnadzor, Stavropol
Email: patomorf@yandex.ru
PhD (Biology), Chief, Laboratory of Phatomorfology Especially Dangerous Contagions Russian Federation
M. V. Kostychenko
The Federal Government Public Health Institution Stavropol Institute for Plague Control of the Rospotrebnadzor, Stavropol
Email: patomorf@yandex.ru
Research Associate, Laboratory of Phatomorfology Especially Dangerous Contagions Russian Federation
N. S. Sarkisian
The Federal Government Public Health Institution Stavropol Institute for Plague Control of the Rospotrebnadzor, Stavropol
Email: patomorf@yandex.ru
Junior Research Associate, Laboratory of Phatomorfology Especially Dangerous Contagions Russian Federation
T. V. Berdnikova
The Federal Government Public Health Institution Stavropol Institute for Plague Control of the Rospotrebnadzor, Stavropol
Email: patomorf@yandex.ru
Junior Research Associate, Laboratory of Brucellosis Russian Federation
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