Characteristics of patients with coronary artery disease and type 2 diabetes mellitus undergoing elective percutaneous coronary intervention
- Authors: Neeshpapa A.G.1, Karetnikova V.N.1,2
-
Affiliations:
- Research Institute for Complex Issues of Cardiovascular Diseases
- Kemerovo State Medical University
- Issue: Vol 16, No 2 (2025)
- Pages: 115-126
- Section: Original study articles
- URL: https://journal-vniispk.ru/2221-7185/article/view/309742
- DOI: https://doi.org/10.17816/CS676532
- EDN: https://elibrary.ru/IVCKLX
- ID: 309742
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Abstract
BACKGROUND: Patients with coronary artery disease (CAD) and type 2 diabetes mellitus (T2DM) represent a distinct group at high cardiovascular risk. Up-to-date information on their management in real-world clinical practice may help identify gaps in care.
AIM: The work aimed to characterize the clinical profile of patients with CAD and T2DM, examine associations with cardiovascular risk factors, and evaluate the adequacy of pharmacotherapy.
METHODS: This study included 50 patients who were electively hospitalized for percutaneous coronary intervention (PCI). Sex, age, and clinical history were recorded, along with anthropometric data. Laboratory parameters included total cholesterol, serum creatinine, blood glucose, and glycated hemoglobin levels. Instrumental assessments included left ventricular ejection fraction by echocardiography and the extent of coronary artery lesions by coronary angiography. Based on these data, a patient profile was constructed, and the adequacy of ongoing pharmacotherapy was evaluated by comparison with data from 2022 in Kemerovo.
RESULTS: Pharmacologic therapy at the time of hospitalization was not optimal in all cases: some patients were not receiving drug classes recommended in standard treatment protocols, and inadequate control of key cardiovascular risk factors was observed (as in the previous study). Target levels of total cholesterol were achieved in only 30 patients (60%), and target levels of glycated hemoglobin in only 26%. Active smoking was reported in 48% of patients, and obesity was observed in 68%.
CONCLUSION: Preparing patients with both CAD and T2DM for elective PCI requires a comprehensive approach to risk factor management. Patients with T2DM undergoing elective PCI often do not receive optimal pharmacologic therapy or achieve adequate control of modifiable risk factors, which warrants close attention and timely correction.
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##article.viewOnOriginalSite##About the authors
Anastasiya G. Neeshpapa
Research Institute for Complex Issues of Cardiovascular Diseases
Author for correspondence.
Email: anastasiyaneeshpapa@mail.ru
ORCID iD: 0000-0002-6808-9959
SPIN-code: 6156-1449
MD, Cand. Sci. (Medicine)
Russian Federation, 6 Academician L.S. Barbarasha blvd, Kemerovo, 650002Victoria N. Karetnikova
Research Institute for Complex Issues of Cardiovascular Diseases; Kemerovo State Medical University
Email: tori1071@mail.ru
ORCID iD: 0000-0002-9801-9839
SPIN-code: 7952-6247
MD, Dr. Sci. (Medicine), Professor
Russian Federation, Kemerovo; KemerovoReferences
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