Development of ways of identification and quantitative definition new вas, wich shows antihypertensive activity

Е А Nepogodina; Непогодина Е А; L А Chekrishkina; Чекрышкина Л А

Development of ways of identification and quantitative definition new вas, wich shows antihypertensive activity

Authors: Nepogodina ЕА¹, Chekrishkina LА¹
Affiliations:
1. State Educational Establishment of Russian Federation«the Perm state pharmaceutical academy of federal agencyon public health and social development»
Issue: No 4 (2009)
Pages: 63-67
Section: Articles
URL: https://journal-vniispk.ru/2313-0245/article/view/337815
ID: 337815

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Abstract

In the Perm state pharmaceutical academy new biologically active substance (ВAS) - N-2(2'-methylphenoxy)-ethylmorpholine hydrochloride, shown high antihypertensive activity in test for cats is synthesized. The complex of researches have leads with the aim of development of ways of identification the method of quantitative definition in not water medium. Estimation validity of technique has bad on parameters: linearity of results, reproducibility and accuracy in analytical area of method. The results of our work have recommended for including in project pharmaceutical paper for investigated ВAS.

Keywords

identification derivative of aryloxyethaneamine, acid-base titration in not water medium, validity

About the authors

Е А Nepogodina

State Educational Establishment of Russian Federation«the Perm state pharmaceutical academy of federal agencyon public health and social development»

Email: somvoz@live.ru <mailto:somvoz@live.ru>
Кафедра фармацевтической химии ФДПО и ФЗО; ГОУ ВПО Росздрава «Пермская государственнаяфармацевтическая академия Федерального агентствапо здравоохранению и социальному развитию»; State Educational Establishment of Russian Federation«the Perm state pharmaceutical academy of federal agencyon public health and social development»

L А Chekrishkina

State Educational Establishment of Russian Federation«the Perm state pharmaceutical academy of federal agencyon public health and social development»

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