A link between solar activity and smoke with hemoblastosis in children
- Authors: Pinaev S.K.1, Chizhov A.Y.2, Pinaeva O.G.1
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Affiliations:
- Far Eastern State Medical University
- Peoples’ Friendship University of Russia
- Issue: Vol 30, No 4 (2022)
- Pages: 597-605
- Section: Safety of human activity
- URL: https://journal-vniispk.ru/2313-2310/article/view/323972
- DOI: https://doi.org/10.22363/2313-2310-2022-30-4-597-605
- ID: 323972
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Abstract
The study of the role of environmental factors in the occurrence of human neoplasms is an important task of medical ecology. An indicator of carcinogenic environmental impacts is childhood tumors due to the predominantly prenatal genesis of tumors at this age. In the structure of childhood oncological morbidity, hemoblastosis predominate. The link between the incidence of childhood leukemia and exposure to ultraviolet radiation, the protective role of sun exposure in relation to the risk of non-Hodgkin’s lymphomas (NHL) and the absence of such in Hodgkin’s lymphoma in children have been established. There is evidence of the connection between childhood hemoblastosis and smoke of various origins. The aim of the study was to evaluate the link between solar activity and smoke with hemoblastosis in the Russian children. We used official data on the incidence of childhood hemoblastosis in Russia in 1997-2020 and data on solar activity from the site of the Royal Observatory of Belgium. The generated dynamic series was subjected to correlation and regression analysis in 11 consecutive iterations with a time delay (lag) from 0 to 10 years in relation to the year of registration of neoplasms. An increase in the incidence of leukemia and a decrease in the incidence of Hodgkin’s lymphoma in the children’s population of Russia have been established. The incidence of NHL in children did not reveal a significant trend. A general pattern was revealed in the form of the connection between childhood leukemia and lymphomas and solar activity, most pronounced in 1997-2008. The increase in the childhood leukemia incidence, taking into account the literature data of the role of exhaust gases in its genesis, can be associated with a threefold increase in the number of cars in Russia during the study period. The reasons for the decrease in the incidence of Hodgkin’s lymphoma require further study. To reduce the risk of hemoblastosis in children, it is advisable to introduce food products into the diet to stimulate autophagy, and transfer factor.
About the authors
Sergey K. Pinaev
Far Eastern State Medical University
Author for correspondence.
Email: pinaev@mail.ru
ORCID iD: 0000-0003-0774-2376
Candidate of Medical Sciences, Associate Professor of the Department of Oncology with a course of surgery and endoscopy of additional postgraduate education
35 Muravyova-Amuskogo St, Khabarovsk, 680000, Russian FederationAlexey Ya. Chizhov
Peoples’ Friendship University of Russia
Email: ma21@mail.ru
ORCID iD: 0000-0003-0542-1552
Doctor of Medicine, Professor, Academician of the Russian Ecological Academy, Professor-Consultant of the Department of Human Ecology and Bioelementology, Institute of Ecology
8/5-423 Podolskoye shosse, Moscow, 115093, Russian FederationOlga G. Pinaeva
Far Eastern State Medical University
Email: pinaeva_og@mail.ru
ORCID iD: 0000-0001-9676-845X
Candidate of Medical Sciences, Associate Professor of the Department of Normal and Pathological Physiology
35 Muravyova-Amuskogo St, Khabarovsk, 680000, Russian FederationReferences
- Agadzhanyan NA, Chizhov AYa, Kim TA. Diseases of civilization. Human Ecology. 2003;(4):8-11. (In Russ.)
- Pinaev SK, Chizhov AYa, Pinaeva OG. Critical periods of adaptation to smoke and solar activity at the stages of ontogeny (Review). Human Ecology. 2021;(11):4-11. https://doi.org/10.33396/1728-0869-2021-11-4-11 (In Russ.)
- Nelson L, Valle J, King G, Mills PK, Richardson MJ, Roberts EM, Smith D, English P. Estimating the Proportion of Childhood Cancer Cases and Costs Attributable to the Environment in California. American Journal of Public Health. 2017;107(5):756-762. https://www.doi.org/10.2105/AJPH.2017.303690
- Coste A, Goujon S, Boniol M, Marquant F, Faure L, Doré JF, Hémon D, Clavel J. Residential exposure to solar ultraviolet radiation and incidence of childhood hematological malignancies in France. Cancer Causes Control. 2015;26(9):1339-49. https://www.doi.org/10.1007/s10552-015-0629-x
- Lombardi C, Heck JE, Cockburn M, Ritz B. Solar UV radiation and cancer in young children. Cancer Epidemiology, Biomarkers and Prevention. 2013;22(6):1118-28. https://www.doi.org/10.1158/1055-9965.EPI-12-1316
- Pedersen C, Johansen C, Schüz J, Olsen JH, Raaschou-Nielsen O. Residential exposure to extremely low-frequency magnetic fields and risk of childhood leukaemia, CNS tumour and lymphoma in Denmark. British Journal of Cancer. 2015;113(9):1370-4. https://www.doi.org/10.1038/bjc.2015.365
- Wong KY, Tai BC, Chia SE, Kuperan P, Lee KM, Lim ST, Loong S, Mow B, Ng SB, Tan L, Tan SY, Tan SH, Tao M, Wong A, Wong GC, Seow A. Sun exposure and risk of lymphoid neoplasms in Singapore. Cancer Causes Control. 2012;23(7):1055-64. https://www.doi.org/10.1007/s10552-012-9974-1
- Hu S, Ma F, Collado-Mesa F, Kirsner RS. Ultraviolet radiation and incidence of non-Hodgkin's lymphoma among Hispanics in the United States. Cancer Epidemiology, Biomarkers and Prevention. 2004;13(1):59-64. https://www.doi.org/10.1158/1055-9965.epi-03-0187
- Dimitrov BD. Non-Hodgkin's lymphoma in US children: biometeorological approach. Folia Medica (Plovdiv). 1999;41(1):29-33. https://pubmed.ncbi.nlm.nih.gov/10462916/
- Dimitrov B. Malignant melanoma of the skin and non-Hodgkin’s lymphoma in USA: a comparative epidemiological study. Folia Medica (Plovdiv). 1999;41(1):121-5. https://pubmed.ncbi.nlm.nih.gov/10462940/
- Petridou ET, Dikalioti SK, Skalkidou A, Andrie E, Dessypris N, Trichopoulos D; Childhood Hematology-Oncology Group. Sun exposure, birth weight, and childhood lymphomas: a case control study in Greece. Cancer Causes Control. 2007;18(9):1031-7. https://www.doi.org/10.1007/s10552-007-9044-2
- SILSO data/image, Royal Observatory of Belgium, Brussels. Available from: http://www.sidc.be/silso/datafiles (accessed: 12.12.2021)
- Ishkov VN. The current 24th cycle of solar activity in the minimum phase: preliminary results and features of development. Cosmic Research. 2020;58(6):436-443. https://www.doi.org/10.31857/S0023420620060060 (In Russ.)
- Pinaev SK, Pinaeva OG, Chizhov AYa. About the role of environmental factors in carcinogenesis. Actual Problems of Ecology and Environmental Management: Cooperation for Sustainable Development and Environmental Safety (APEEM 2020). E3S Web of Conferences. 169, 04003. 2020. https://doi.org/10.1051/e3sconf/202016904003
- Saliev T, Begimbetova D, Masoud AR, Matkarimov B. Biological effects of non-ionizing electromagnetic fields: Two sides of a coin. Progress in Biophysics and Molecular Biology. 2019;141:25-36. https://doi.org/10.1016/j.pbiomolbio.2018.07.009
- IARC Monographs on the Identification of Carcinogenic Hazards to Humans. List of Classifications. Agents Classified by the IARC Monographs. Vol. 1-127. Available from: https://monographs.iarc.fr/list-of-classifications Last updated: 2020-06-26 08.45am (CEST). (accessed: 20.06.2021).
- Heck JE, Park AS., Qiu J, Cockburn M, Ritz B. Risk of leukemia in relation to exposure to ambient air toxics in pregnancy and early childhood. International Journal of Hygiene and Environmental Health. 2014;217(6):662-8. https://doi.org/10.1016/j.ijheh.2013.12.003
- McKinney PA, Fear NT, Stockton D. UK Childhood Cancer Study Investigators. Parental occupation at periconception: findings from the United Kingdom Childhood Cancer Study. Occupational and Environmental Medicine. 2003;60(12):901-9. https://doi.org/10.1136/oem.60.12.901
- Ghosh JK, Heck JE, Cockburn M, Su J, Jerrett M, Ritz B. Prenatal exposure to traffic-related air pollution and risk of early childhood cancers. American Journal of Epidemiology. 2013;178(8):1233-9. https://doi.org/10.1093/aje/kwt129
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