CHARACTERISTICS OF PATIENTS WITH CHRONIC VIRAL HEPATITIS IN THE SAMARA REGION

The purpose of the research is to give description of patients with CVH observed in the Samara regional hepatological centre of Samara State Medical University and to identify groups for antiviral therapy based on its potential effectiveness for known predictors: gender, age, presence of HBeAg, viral load, genotype of the virus. 336 of CVH patients aged 18 to 78 years with disease duration from 3 to 12 years were observed. Examination of patients by the standard criteria for patients with chronic viral hepatitis showed that among patients with chronic viral hepatitis В in Samara region the main group of patients is HBV DNA «+», HBeAg-negative, genotype D. Among 336 patients 65.5% of the observed patients are subject to antiviral therapy, 18.4% of which have high probability of achieving SVR. In the rest 47.1% of patients it is necessary to consider the ratio of cost of treatment, its effectiveness, motivation of the patient that requires an individual approach in each case.

chronic viral hepatitis B, Samara region, antiviral therapy