Email this article Allografts for surgery in the closure of nasal septal intraoperative defects
- Authors: Shelikhovskaia M.A.1, Syroezhkin F.A.1, Tipikin V.P.1, Vinichenko K.V.1, Kulish A.V.1, Kovtun S.V.1
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Affiliations:
- Military Medical Academy named after S.M. Kirov
- Issue: Vol 20, No 1-2 (2020)
- Pages: 37-43
- Section: Clinical Medicine
- URL: https://journal-vniispk.ru/2410-3764/article/view/54468
- DOI: https://doi.org/10.17816/2072-2354.2020.20.1.44-48
- ID: 54468
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Abstract
Surgical correction of the deviation of nasal septum is the most frequently performed surgical interventions in Otorhinolaryngology departments. Sometimes such operations can be complicated by an intraoperative defect in the nasal septum, which is not always possible to close with autogenous tissue. That’s why it has become important to use new allogenic transplant materials in the treatment of these defects. The purpose of the study was to evaluate the effectiveness of allografts (allogeneic fascia and allogenic cartilage treated by Alloplant technology) in closure of intraoperative defects of the nasal septum. The treatment was performed to 40 patients aged 24–55 who developed defect of the mucous membrane of the nasal septum during the operation for nasal spetum deviation. Patients were randomly divided into two groups of 20 people. The 1st group included patients whose allogenic transplantat materials were used in addition to their own tissues during the closure of the defect. The 2nd group consisted of patients whose autogenous tissues were used during the operation. The data of functional state of the nasal mucosa and the anatomical integrity of the nasal septum of all patients before treatment, one month and one year after the treatment were checked and compared. It was revealed that allografts (allogenic fascia and allogenic cartilage treated by Alloplant technology) demonstrated an anti-inflammatory effect, and their use in closing of intraoperative defects of the nasal septum is more effective. This procedure also accelerates improvement of the functional activity of the nasal mucosa in comparison with the use of autogenous tissues solely.
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##article.viewOnOriginalSite##About the authors
Mariia A. Shelikhovskaia
Military Medical Academy named after S.M. Kirov
Author for correspondence.
Email: mariy_sh94@mail.ru
ORCID iD: 0000-0001-8514-9362
Postgraduate Student, Department of Otorhinolaryngology
Russian Federation, Saint PetersburgFedor A. Syroezhkin
Military Medical Academy named after S.M. Kirov
Email: lor_vma@mail.ru
ORCID iD: 0000-0002-2113-3377
Doctor of Medical Sciences, Lecturer of the Department of Otorhinolaryngology
Russian Federation, Saint PetersburgVasily P. Tipikin
Military Medical Academy named after S.M. Kirov
Email: basiltipikin@yandex.ru
Candidate of Medical Sciences, Lecturer of the Department of Otorhinolaryngology
Russian Federation, Saint PetersburgKsenia V. Vinichenko
Military Medical Academy named after S.M. Kirov
Email: vinichenkokv@mail.ru
ENT Specialist of the Clinic of Otorhinolaryngology
Russian Federation, Saint PetersburgAlexandra V. Kulish
Military Medical Academy named after S.M. Kirov
Email: vbx.07@mail.ru
Resident of the Department of Otorhinolaryngology
Russian Federation, Saint PetersburgSofya V. Kovtun
Military Medical Academy named after S.M. Kirov
Email: ksv91@inbox.ru
Resident of the Department of Otorhinolaryngology
Russian Federation, Saint PetersburgReferences
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