Email this article The development of approaches to the standardization of the syringa vulgaris leaves
- Authors: Serebryakova A.D.1, Kurkin V.A.1
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Affiliations:
- Samara State Medical University
- Issue: Vol 20, No 1-2 (2020)
- Pages: 158-163
- Section: Pharmacy
- URL: https://journal-vniispk.ru/2410-3764/article/view/54535
- DOI: https://doi.org/10.17816/2072-2354.2020.20.1.158-163
- ID: 54535
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Abstract
The article studies the problems of phytochemical research of Syringa vulgaris L. leaves, which are a perspective raw material containing flavonoids. As a result of the study, the optimal conditions for the extraction of flavonoids in the leaves of Syringa vulgaris were determined: 70% ethanol was used as an extragent; the ratio “raw material – extragent” was 1 : 50; extraction time was 45 min; the degree of fineness was 1 mm. The method of quantitative determination of the total flavonoids in the leaves of Syringa vulgaris by means of differential spectrophotometry with the use of state standard sample of rutin at a wave length of 412 nm was developed. The content of the total flavonoids for Syringa vulgaris leaves varies from 2,76% to 3,89% (calculated with reference to rutin). The error of a single determination with a 95% confidence probability is 6,12%.
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##article.viewOnOriginalSite##About the authors
Anastasiya D. Serebryakova
Samara State Medical University
Author for correspondence.
Email: lazymoon93@mail.ru
Postgraduate student, Department of Pharmacognosy with Botany and Bases of Phytotherapy
Russian Federation, SamaraVladimir A. Kurkin
Samara State Medical University
Email: kurkinvladimir@yandex.ru
доктор фармацевтических наук, профессор, заведующий кафедрой фармакогнозии с ботаникой и основами фитотерапии
Russian Federation, SamaraReferences
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