Linear IgA-dependent bullous dermatosis as a rare type of vancomycin therapy complication: a clinical case
- Authors: Safronenko A.V.1, Gantsgorn E.V.1, Polyakova V.I.1, Gubin E.V.1, Rashkova E.V.1, Tuganov I.V.1
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Affiliations:
- Rostov State Medical University of the Ministry of Healthcare of Russia
- Issue: Vol 10, No 2 (2024)
- Pages: 72-76
- Section: CLINICAL CASE
- URL: https://journal-vniispk.ru/2412-4036/article/view/274518
- DOI: https://doi.org/10.18565/therapy.2024.2.72-76
- ID: 274518
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Abstract
Any antibacterial pharmacotherapy is characterized by a certain profile of efficacy and safety. At the same time, some antibiotics, and vancomycin in particular, have a high degree of toxicity, and therefore their use is associated with a high risk of developing various adverse reactions. This, in turn, requires extremely strict adherence to the principles of rational antibiotic therapy, clear indications for prescribing the drug, and a careful assessment of the dynamics of the patient’s clinical status. The aim of the article is to describe a clinical case of the development of linear IgA-dependent bullous dermatosis while taking vancomycin in a patient from the “vulnerable” group. Improving doctors’ competence concerning antibacterial therapy complications, including rare ones, in our opinion, will make it possible to timely adjust the tactics of managing “difficult” patients in order to increase its safety.
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##article.viewOnOriginalSite##About the authors
Andrey V. Safronenko
Rostov State Medical University of the Ministry of Healthcare of Russia
Author for correspondence.
Email: andrejsaf@mail.ru
ORCID iD: 0000-0003-4625-6186
MD, Dr. Sci. (Medicine), associate professor, head of the Department of Pharmacology and Clinical Pharmacology
Russian Federation, 344022, Rostov-on-Don, 29 Nakhichevansky LaneElena V. Gantsgorn
Rostov State Medical University of the Ministry of Healthcare of Russia
Email: gantsgorn@inbox.ru
ORCID iD: 0000-0003-0627-8372
MD, PhD (Medicine), associate professor, associate professor of the Department of Pharmacology and Clinical Pharmacology
Russian Federation, 344022, Rostov-on-Don, 29 Nakhichevansky Lane
Victoriya I. Polyakova
Rostov State Medical University of the Ministry of Healthcare of Russia
Email: polyakowa.vi@yandex.ru
ORCID iD: 0000-0002-8886-8984
student of Pediatric Faculty
Russian Federation, 344022, Rostov-on-Don, 29 Nakhichevansky LaneEvgeniy V. Gubin
Rostov State Medical University of the Ministry of Healthcare of Russia
Email: dr.gubin201@ya.ru
ORCID iD: 0009-0009-3584-9147
student of Faculty of General Medicine
Russian Federation, 344022, Rostov-on-Don, 29 Nakhichevansky LaneEkaterina V. Rashkova
Rostov State Medical University of the Ministry of Healthcare of Russia
Email: ekaterina.raschkova2002@gmail.com
ORCID iD: 0009-0003-5619-5484
student of Faculty of General Medicine
Russian Federation, 344022, Rostov-on-Don, 29 Nakhichevansky LaneIriston V. Tuganov
Rostov State Medical University of the Ministry of Healthcare of Russia
Email: anhel.kallen@mail.ru
ORCID iD: 0009-0006-3325-3276
student of Pediatric Faculty
Russian Federation, 344022, Rostov-on-Don, 29 Nakhichevansky LaneReferences
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