Email this article Macromicroscopic anatomy of the placenta after in vitro fertilization
- Authors: Mitrofanova I.V.1, Lutsay E.D.1
-
Affiliations:
- Orenburg State Medical University
- Issue: Vol 10, No 1 (2025)
- Pages: 10-16
- Section: Human Anatomy
- URL: https://journal-vniispk.ru/2500-1388/article/view/286959
- DOI: https://doi.org/10.35693/SIM642560
- ID: 286959
Cite item
Abstract
Aim – to obtain new data on the macromicroscopic anatomy of the placenta in pregnancy after in vitro fertilization.
Material and methods. The work was performed on 60 placentas after in vitro fertilization. Morphologic study was performed on 30 placentas after IVF. Two fragments were isolated from each placenta – from the marginal and central zone. Serial histotopograms stained according to the Van Gieson method were made. Ultrasound examinations were performed at 20.4-21.1 weeks of gestation. The slice size of the marginal sinus and the area of the placenta were studied.
Results. The median thickness of the choroidal lamina was 250 μm in the central zone and 166.5 μm in the marginal zone; the median vascular diameter was 1653 μm in the central zone and 1040 μm at the edge of the placenta. The median basal lamina thickness was 300 μm in the central zone and 210 μm at the margin. The median length of septa in the central and marginal zones of the placenta was 19893.5 μm and 16007 μm, respectively, and the width of septa was 300 μm in the central zone and 240 μm in the marginal zone. At 20-22 weeks, ultrasound scans can reveal the marginal sinus. The slice shape of the marginal sinus varied from triangular to irregular: the frequency of triangular shape was 40%, arrow-shaped – 30%, irregular shape – 30%.
Conclusion. Thus, it is possible to distinguish three zones in the placenta after IVF at the macromicroscopic level: subchorionic, middle and suprabasal, which have their own histotopographic picture.Quantitative characteristics of placental structures are connected to the place of umbilical cord attachment and have differences in the marginal and central zones.
The shape of the marginal sinus when assessed by ultrasound scanning is different (triangular, arrow-shaped, irregular), with the largest area sizes noted for the irregularly shaped marginal sinus.
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##article.viewOnOriginalSite##About the authors
Irina V. Mitrofanova
Orenburg State Medical University
Author for correspondence.
Email: iv.mitrofanova@mail.ru
ORCID iD: 0000-0002-8470-9134
MD, Dr. Sci. (Medicine), Professor of the Department of Human Anatomy
Russian Federation, OrenburgElena D. Lutsay
Orenburg State Medical University
Email: elut@list.ru
ORCID iD: 0000-0002-7401-6502
MD, Dr. Sci. (Medicine), Professor of the Department of Human Anatomy
Russian Federation, OrenburgReferences
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