Email this article Immunological and hemostasiological aspects of pathogenesis of obliterating atherosclerosis of arteries of the lower extremities
- Authors: Korymasov E.A.1,2, Krivoshchekov E.P.1, Kazantsev A.V.1,2, Pribytkov D.L.2
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Affiliations:
- Samara State Medical University
- Samara Regional Clinical Hospital named after V.D. Seredavin
- Issue: Vol 6, No 3 (2021)
- Pages: 69-72
- Section: Surgery
- URL: https://journal-vniispk.ru/2500-1388/article/view/81422
- DOI: https://doi.org/10.35693/2500-1388-2021-6-3-69-72
- ID: 81422
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Abstract
Objectives – to study the changes in the immunological status and hemostatic system in patients with obliterating atherosclerosis of the lower limb arteries with the damage to the femoral-popliteal-tibial segment.
Material and methods. A comprehensive study of the cytokine status and hemostatic system in patients with obliterating atherosclerosis of lower limb arteries with lesions of the femoral-popliteal tibia segment was carried out.
Results. The progressive course of obliterating atherosclerosis is often associated with an increased content of cytokines (IL-1â, IL-6, IL-8, TNFá), as well as with the phenomena of hypercoagulation (increased platelet aggregation activity, shortened APTT, CT, TT, increased fibrinogen content), SFMCs, D-dimer).
Conclusion. The study of the immunological status and hemostatic system should be performed in all patients with obliterating atherosclerosis of the lower limb arteries in order to adequately medically correct and prevent postoperative complications.
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##article.viewOnOriginalSite##About the authors
Evgenii A. Korymasov
Samara State Medical University; Samara Regional Clinical Hospital named after V.D. Seredavin
Email: korymasov@mail.ru
PhD, Professor, Head of the Department of Surgery of the Institute of Professional Education
Russian Federation, Samara; 159 Tashkentskaya st., Samara, 443095Evgenii P. Krivoshchekov
Samara State Medical University
Email: walker02@mail.ru
ORCID iD: 0000-0001-9780-7748
PhD, Professor, Head of the training department of the Department of Surgery of the Institute of Professional Education
Russian Federation, SamaraAleksandr V. Kazantsev
Samara State Medical University; Samara Regional Clinical Hospital named after V.D. Seredavin
Author for correspondence.
Email: dockazantsev@mail.ru
ORCID iD: 0000-0002-9401-1506
PhD, Associate professor, Department of Surgery of the Institute of Professional Education, Cardiovascular surgeon of Department of vascular surgery
Russian Federation, Samara; 159 Tashkentskaya st., Samara, 443095Dmitrii L. Pribytkov
Samara Regional Clinical Hospital named after V.D. Seredavin
Email: pribytkovreaviz@mail.ru
ORCID iD: 0000-0001-7937-7502
Head of the operational unit, physician, cardiovascular surgeon of the Department of Vascular surgery
Russian Federation, 159 Tashkentskaya st., Samara, 443095References
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