The effect of the composition of hepatoprotective action on biochemical and morphostructural changes in the body of laying hens under thermal stress
- Authors: Drozdova L.I.1, Krasnoperov A.S.1, Oparina O.Y.1, Malkov S.V.1, Belousov A.I.1, Chernitskiy A.E.1
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Affiliations:
- Ural Federal Agrarian Scientific Research Center, Ural Branch of the Russian Academy of Sciences
- Issue: No 4 (2024)
- Pages: 61-66
- Section: Animal science and veterinary medicine
- URL: https://journal-vniispk.ru/2500-2627/article/view/267127
- DOI: https://doi.org/10.31857/S2500262724040113
- EDN: https://elibrary.ru/FKTJFQ
- ID: 267127
Cite item
Abstract
To reduce the negative effects of hyperthermia on the body of farm animals and poultry, various drugs and feed additives are currently used. Which do not have sufficiently adaptogenic and antitoxic properties. We studied the effect of a hepatoprotective composition consisting of dried live yeast, amorphous silicon dioxide, propylene glycol, calcium propionate, ascorbic acid, manganese, copper and zinc chelates, methionine and choline chloride on the variability of biochemical and morphological parameters of the body of laying hens under temperature stress. It was simulated by increasing the air temperature in a building where laying hens were kept from 18.0 ± 1.0 °C to 28.0 ± 1.0 °C for 48 hours. Due to hyperthermia, changes in biochemical and morphofunctional parameters were observed in the tissues and organs of birds. The obtained values of the biochemical parameters of blood serum in the birds of the control group indicated the intensity of the adaptive capabilities of their body. A complex of morphological changes confirmed a violation of protein metabolism and the regenerative-compensatory process. Pathological changes in the structure of the duodenum, characteristic of catarrhal-necrotic duodenitis, were identified. The stress reaction was also reflected in the condition of the heart muscle, in which an inflammatory process developed against the background of granular dystrophy of cardiomyocytes. The results of biochemical studies of blood serum in birds of the experimental group indicated an increase in the anti-stress response to a temperature stimulus under the influence of the studied composition (tendency to increase glucose and calcium, increase alkaline phosphatase activity by 47.4 %). The introduction of a hepatoprotective composition into the diet of laying hens during periods of temperature stress did not lead to disruption of the structure of tissues and organs, preserving cellular metabolic mechanisms. The
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About the authors
L. I. Drozdova
Ural Federal Agrarian Scientific Research Center, Ural Branch of the Russian Academy of Sciences
Author for correspondence.
Email: marafon.86@list.ru
доктор ветеринарных наук
Russian Federation, 620142, Ekaterinburg, ul. Belinskogo, 112aA. S. Krasnoperov
Ural Federal Agrarian Scientific Research Center, Ural Branch of the Russian Academy of Sciences
Email: marafon.86@list.ru
кандидат ветеринарных наук
Russian Federation, 620142, Ekaterinburg, ul. Belinskogo, 112aO. Yu. Oparina
Ural Federal Agrarian Scientific Research Center, Ural Branch of the Russian Academy of Sciences
Email: marafon.86@list.ru
кандидат ветеринарных наук
Russian Federation, 620142, Ekaterinburg, ul. Belinskogo, 112aS. V. Malkov
Ural Federal Agrarian Scientific Research Center, Ural Branch of the Russian Academy of Sciences
Email: marafon.86@list.ru
кандидат ветеринарных наук
Russian Federation, 620142, Ekaterinburg, ul. Belinskogo, 112aA. I. Belousov
Ural Federal Agrarian Scientific Research Center, Ural Branch of the Russian Academy of Sciences
Email: marafon.86@list.ru
доктор ветеринарных наук
Russian Federation, 620142, Ekaterinburg, ul. Belinskogo, 112aA. E. Chernitskiy
Ural Federal Agrarian Scientific Research Center, Ural Branch of the Russian Academy of Sciences
Email: marafon.86@list.ru
доктор биологических наук
Russian Federation, 620142, Ekaterinburg, ul. Belinskogo, 112aReferences
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