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Vol 7, No 3 (2017)
- Year: 2017
- Articles: 2
- URL: https://journal-vniispk.ru/2634-8276/issue/view/13570
Article
Determination of proteins in blood. Part 3: Systematization of methods for the determination of protein compounds in blood
Abstract
The review presents a chronological development of procedures for determining the concentrations of total protein and albumin; total concentration of globulins; concentrations of subfractions, classes, and subclasses of globulins; and total concentrations of globulin subclasses in human blood. A brief overview of these procedures and the results of their comparative tests in medical examination of patients are given. The considered procedures are systematized; their advantages and disadvantages are discussed. It is noted that procedures for measuring the concentration of total protein, albumin, and globulin classes in plasma, serum, and whole blood are widely used in modern clinical diagnostic laboratories when performing routine assays. The concentrations of globulin subclasses and total concentrations of globulin subclasses in blood are mainly determined in biomedical research. Procedures for measuring the concentration of total globulins and globulin subfractions in plasma and serum are of historical importance and now are barely applied in clinical and diagnostic laboratories.
261-333
Negative photochromism in organic systems
Abstract
The results of studies on negative photochromism of compounds and systems have been analyzed for the first time. It has been shown that the majority of studies deal with photochromic spiro compounds (spiropyrans and spirooxazines) whose negative photochromism is caused mainly by molecular structure, polarity and acidity of the medium, and complexation with metal ions. Among other most studied compounds, negative photochromism has been observed for photochromic dihydropyrenes. Photoisomerization of certain compounds, in particular, thioindigoid dyes, provides a photoinduced hypsochromic shift of absorption bands with substance color change.
334-371