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Том 9, № 2 (2019)
- Год: 2019
- Статей: 2
- URL: https://journal-vniispk.ru/2634-8276/issue/view/13579
Article
Recent Progress in Synthesis, Structure and Biological Activities of Phenothiazine Derivatives
Аннотация
The phenothiazine nucleus is one of the most important and trusted heterocyclic ring, which is commonly found in natural products and medicinal agents. It was discovered during the 1940s, since many scientists were found various newer derivatives and established their biological activities. The recently developed phenothiazine derivatives were exhibiting significant activities such as tranquillizer, antibacterial, antiparkinsonian, antifungal, anticancer, antiviral, anti-inflammatory, antihistaminic, anti-malarial, anti-filarial, trypanocidal, anticonvulsant, analgesic, immunosuppressive and multidrug resistance reversal properties. In the presented study, an attempt had been made to systematize the recent research finding of many newer phenothiazine derivatives including method of synthesis, structure and evaluated in vitro and in vivo promising biological activities and pharmacological properties. This review emphasises the two decades of research work on newer synthesis, structure and biological activities of different phenothiazine derivatives.
95-126
Synthesis and Properties of Zinc Oxide Nanoparticles: Advances and Prospects
Аннотация
The physical, chemical, and biological methods for the synthesis of zinc oxide nanoparticles are considered; their advantages and disadvantages are analyzed. The relationship between the method of synthesis and the properties of the systems obtained is shown. The unique optical and antibacterial properties of zinc oxide nanoparticles and the relevant areas of their practical applications are discussed. The dependence of the antibacterial properties of zinc oxide on the shape and size of its particles is revealed.
127-152