Application of Magnetic Nanoparticles in Immunoassay

Abstract

Complexes of magnetic nanoparticles with antibodies are used for the selective and highly sensitive detection in medical diagnostics, environmental monitoring, and the product quality and safety control. Magnetic nanoparticles are applied as controllable carriers to concentrate samples, as a solid phase in assays, or as labels detected by virtue of their magnetic, optical, or other properties. This review covers the results of recent studies, including methods for the preparation of analytical reagents, new assays, and techniques for the detection of magnetic nanoparticles.