Development of paradigms for the diagnosis of "covert cognition" and cognitive motor dissociation in patients with chronic disorders of consciousness

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Abstract

The detection of signs of consciousness in patients with chronic disorders of consciousness is a complex clinical task. In recent decades, instrumental methods have been used to improve the accuracy of diagnostics. The phenomenon of «covert cognition» and cognitive motor dissociation have been demonstrated in a small proportion of patients in studies using instrumental methods in combination with different paradigms. This article describes the main features of the diagnostic paradigms used for such purposes. Currently, the development of its own complex of paradigms is held at the Research Center of Neurology collaboratively with group of neuropsychologists from Lomonosov Moscow State University. The general characteristics of this complex of paradigms are indicated. The practical significance of detecting the phenomenon of «covert cognition» and cognitive motor dissociation in patients with chronic disorders of consciousness is discussed.

About the authors

Anastasiia N. Cherkasova

Research Center of Neurology; Lomonosov Moscow State University

Email: cherka.sova@mail.ru
ORCID iD: 0000-0002-7019-474X
SPIN-code: 1226-8004
Russian Federation, 80 Volokolamsk sh., Moscow, 125367; Moscow

Kseniia A. Yatsko

Research Center of Neurology; Lomonosov Moscow State University

Author for correspondence.
Email: kseniia.a.ilina@gmail.com
ORCID iD: 0000-0002-3014-4350

MD

Russian Federation, 80 Volokolamsk sh., Moscow, 125367; Moscow

Maria S. Kovyazina

Research Center of Neurology; Lomonosov Moscow State University

Email: kms130766@mail.ru
ORCID iD: 0000-0002-1795-6645
SPIN-code: 1570-8446

Dr. Sci. (Psychology), Professor, Corresponding Member of RAO

Russian Federation, 80 Volokolamsk sh., Moscow, 125367; Moscow

Nataliya A. Varako

Research Center of Neurology; Lomonosov Moscow State University

Email: kms130766@mail.ru
ORCID iD: 0000-0002-8310-8169
SPIN-code: 4073-2560

Cand. Sci. (Psychology)

Russian Federation, 80 Volokolamsk sh., Moscow, 125367; Moscow

Marina V. Krotenkova

Research Center of Neurology

Email: krotenkova_mrt@mail.ru
ORCID iD: 0000-0003-3820-4554
SPIN-code: 9663-8828

MD, Dr. Sci. (Med.)

Russian Federation, 80 Volokolamsk sh., Moscow, 125367

Elena I. Kremneva

Research Center of Neurology

Email: kremneva@neurology.ru
ORCID iD: 0000-0001-9396-6063
SPIN-code: 8799-8092

MD, Cand. Sci. (Med.)

Russian Federation, 80 Volokolamsk sh., Moscow, 125367

Amayak G. Broutian

Research Center of Neurology

Email: abroutian@mail.ru
ORCID iD: 0000-0002-6381-2925
SPIN-code: 1540-7150

MD, Cand. Sci. (Med.)

Russian Federation, 80 Volokolamsk sh., Moscow, 125367

Yulia V. Ryabinkina

Research Center of Neurology

Email: ryabinkina11@mail.ru
ORCID iD: 0000-0001-8576-9983
SPIN-code: 5044-2701

MD, Dr. Sci. (Med.)

Russian Federation, 80 Volokolamsk sh., Moscow, 125367

Andrey A. Belkin

Ural State Medical University

Email: belkin@neuro-ural.ru
ORCID iD: 0000-0002-0544-1492
SPIN-code: 6683-4704

MD, Dr. Sci. (Med.), Professor

Russian Federation, Yekaterinburg

Vladimir A. Belkin

Ural State Medical University

Email: vbelkin@neuro-ural.ru
ORCID iD: 0000-0002-4043-743X
SPIN-code: 4402-0608

MD

Russian Federation, Yekaterinburg

Natalia A. Suponeva

Research Center of Neurology

Email: nasu2709@mail.ru
ORCID iD: 0000-0003-3956-6362
SPIN-code: 3223-6006

MD, Dr. Sci. (Med.), Professor, Corresponding Member of the Russian Academy of Sciences

Russian Federation, 80 Volokolamsk sh., Moscow, 125367

Michael А. Piradov

Research Center of Neurology

Email: dir@neurology.ru
ORCID iD: 0000-0002-6338-0392
SPIN-code: 2860-1689

MD, Dr. Sci. (Med.), Professor, Academician of the Russian Academy of Sciences

Russian Federation, 80 Volokolamsk sh., Moscow, 125367

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Copyright (c) 2021 Cherkasova A.N., Yatsko K.A., Kovyazina M.S., Varako N.A., Krotenkova M.V., Kremneva E.I., Broutian A.G., Ryabinkina Y.V., Belkin A.A., Belkin V.A., Suponeva N.A., Piradov M.А.

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