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Post a Comment Comorbid diseases and conditions of patients with a novel coronavirus infection COVID-19, who died in infectious hospital
- Authors: Khokhlova Y.A.1, Markelova L.N.2, Titova N.E.1
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Affiliations:
- Smolensk State Medical University
- Clinical Hospital № 1
- Issue: Vol 39, No 5 (2022)
- Pages: 12-20
- Section: Original studies
- URL: https://journal-vniispk.ru/PMJ/article/view/112471
- DOI: https://doi.org/10.17816/pmj39512-20
- ID: 112471
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Abstract
Objective. To analyze the comorbid diseases and conditions in patients with a novel coronavirus infection COVID-19, who died in the infectious hospital.
Materials and methods. Analysis of 1202 postmortem epicrises and protocols of pathologicoanatomic study of patients, who died in the infectious hospital of Smolensk on the basis of Clinical Hospital № 1 was carried out.
Results. There prevailed elderly and old patients – 81.5 %, most of them suffered from cardiovascular diseases (CVD), first of all ischemic heart disease – 92 % and arterial hypertension – 94.8 %. The most frequent risk factors/comorbid background of CVD were obesity (53.7 %), type 2 diabetes mellitus – 29.8 %. Practically all patients suffered from chronic heart failure, each third – 2b–3 stage, III–IV functional class (30.1 %). The basic comorbid diseases/conditions during hospitalization period were myocardial infarction (3.8 %), acute coronary syndrome (5.2 %), cerebral stroke (6.1 %), pulmonary embolism (4.3 %), atrial fibrillation paroxysm (8.7 %), myocarditis/pericarditis (3.8 %). In 43.1 % of patients, the comorbid pathology was on the foreground as a concurrent/concomitant/basic disease (as a basic diseases – in 12.9 % of patients).
Conclusions. Among the dead patients with COVID-19 there prevail elderly and old patients, burdened for comorbidity. Most of all, cardiovascular pathology, complicated by heart failure and associated with obesity and type 2 diabetes mellitus has an impact of the outcome of disease.
The comorbid diseases/conditions during hospitalization are determined, as a rule, by vascular thromboses of various localizations. In every tenth patient, the comorbid pathology was the direct cause of death.
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##article.viewOnOriginalSite##About the authors
Yu. A. Khokhlova
Smolensk State Medical University
Author for correspondence.
Email: kho.julia@list.ru
Candidate of Medical Sciences, Associate Professor, Department of Faculty Therapy
Russian Federation, SmolenskL. N. Markelova
Clinical Hospital № 1
Email: kho.julia@list.ru
Deputy Chief Physician for Medical Work
Russian Federation, SmolenskN. E. Titova
Smolensk State Medical University
Email: kho.julia@list.ru
Candidate of Medical Sciences ,Associate Professor, Department of General Medical Practice, Polyclinic Therapy with Course of Geriatrics, Faculty of Additional Professional Education
Russian Federation, SmolenskReferences
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