PECULIARITIES OF COGNITIVE STATUS IN YOUNG WOMEN WITH MILD AND MODERATELY SEVERE IRON-DEFICIENCY ANEMIA

Aim. To give the comparative characteristic of cognitive status in women depending on presence of iron-deficiency anemia, to study the possibilities of restoring the available cognitive deficiency against the background of anemia correction with iron preparations. Materials and methods. The study included 40 women aged 18 to 44 years, who were diagnosed mild and moderately severe iron-deficiency anemia. Complex clinicolaboratory and neuropsychical examination was carried out using MoCa test, Gotland, Spilberger-Hanin scales, asthenia estimation scale (MFI-20) before anemia therapy, 12 and 24 weeks after it. Comparison was fulfilled with the control group of nonanemic women. Results. When analyzing cognitive functions before anemic therapy in the group of mild and moderately severe iron-deficiency anemic patients aged 18 to 44 years, we detected mild cognitive disorders, predominantly attention, speech and memory functions. Anemia correction, normalization of hemoglobin, iron and blood serum ferritin against the background of anemia therapy with iron preparation were associated with reduced manifestation of cognitive disorders. Conclusions. The study results indicated that ferrotherapy reliably restores the available cognitive deficiency in young patients diagnosed mild and moderately severe iron-deficiency anemia. However, despite restoration of hematological indices, correction of cognitive deficiency and improvement of patients’ health status, asthenic component is preserved.

Cognitive status, iron-deficiency anemia, asthenia, young age, female sex