Email this article 
Post a Comment Lyme borreliosis: clinical and epidemiological features of its course in the territory of large industrial center of Western Urals
- Authors: Nikolenko V.V.1, Vorobyova N.N.1, Merkuryeva E.V.2, Nikolenko A.V.1, Suslina O.A.1
-
Affiliations:
- E.A. Vagner Perm State Medical University
- Perm Regional Clinical Infectious Hospital
- Issue: Vol 37, No 4 (2020)
- Pages: 46-53
- Section: Original studies
- URL: https://journal-vniispk.ru/PMJ/article/view/42304
- DOI: https://doi.org/10.17816/pmj37446-53
- ID: 42304
Cite item
Full Text
Abstract
Objective. Since the territory of the Western Urals is widely known for its high morbidity and mortality rates associated with tick-borne infections, including ixodic tick-borne borreliosis, the study was aimed at estimation of the role of specific prevention in the prevalence of ITB.
Materials and methods. A continuous retrospective clinical and laboratory analysis of 1214 adult patients admitted to Perm Regional Clinical Infectious Disease Hospital with lyme - borreliosis in 2012-2019 was carried out.
Results. The disease is registered more often in persons over 50 years old, infection mainly occurs while visiting forests and park zones that requires the use of means of protection to reduce the number of the carriers of infection. Every third patient has mixed infection, where pathogens circulating in the ticks of the given territory of the Western Urals are combined. The increase in the number of non-erythemic forms in the recent years is probably associated with the development of immunodeficiency in the population of the industrial center, as well as with the use of more sensitive and informative methods of laboratory diagnostics.
Conclusions. Specific prophylaxis is highly effective, helping to prevent infection in more than 90% of cases.
Keywords
Full Text
##article.viewOnOriginalSite##About the authors
Vera V. Nikolenko
E.A. Vagner Perm State Medical University
Author for correspondence.
Email: vvn73@yandex.ru
MD, PhD, Professor, Department of Infectious Diseases; Vorobyova N.N. – MD, PhD, Professor, Head of Department of Infectious Diseases
Russian Federation, PermNatalia N. Vorobyova
E.A. Vagner Perm State Medical University
Email: infec-perm@mail.ru
MD, PhD, Professor, Head of Department of Infectious Diseases
Russian Federation, PermElena V. Merkuryeva
Perm Regional Clinical Infectious Hospital
Email: merkureva1975@mail.ru
Head of CE and ICH Center
Russian Federation, PermAndrey V. Nikolenko
E.A. Vagner Perm State Medical University
Email: avn72@mail.ru
Candidate of Medical Sciences, Associate Professor, Chief Non-staff Anaesthesiologist-Reanimatologist of MOH PK, Head of Department of Anesthesiology, Reanimatology and Emergency Medical Care
Russian Federation, PermOlga A. Suslina
E.A. Vagner Perm State Medical University
Email: o.gigiena@bk.ru
Candidate of Medical Sciences, Associate Professor, Department of Common Hygiene and Human Ecology
Russian Federation, PermReferences
- Bondarenko A.L., Zykova I.V., Abbaso- va S.V., Tihomolova E.G., Nekhoroshkina E.L. Mixed infection of tick-borne encephalitis and ixodic tick-borne borreliosis. Infekcionnye bolezni 2011; 4: 54–63 (in Russian).
- Natural focal infections transmitted by ixodid ticks. Pod red. A.L. Gincburga, V.N. Zlobina. Moscow: Nauka 2013; 463 (in Russian).
- Korenberg Je.I., Nikolenko V.V., Vorob'eva N.N. Indirect reaction of immunofluorescence in laboratory diagnosis of ITB. Med. parazitologija i parazitarnye bolezni 2000; 3: 19–23 (in Russian).
- Nikolenko V.V., Vorob'eva N.N., Merkur'eva E.V., Nikolenko A.V., Suslina O.A., Okishev M.A., Rozhkova D.K. Clinical and epidemiological features of the course of tick-borne encephalitis in the Perm region. Perm medicinskij zhurnal 2020; 37 (3): 18–25 (in Russian).
- Baranova N.S., Spirin N.N., SHipova E.G., Stepanov I.O. Damage to the nervous system in the late stages of Lyme borreliosis. ZHurnal nevrologii i psihiatrii 2010; 2: 90–96 (in Russian).
- Kon'kova-Rejdman A.B. Tick-borne neuroinfections: clinical characteristics, immunopathogenesis and new pharmacotherapeutic strategies. Terapevticheskij arhiv 2016; 11: 55–61 (in Russian).
- Mel'nikova O.V., Andaev E.I. Epidemiological manifestations of tick-borne encephalitis and ixodic tick-borne borreliosis in Irkutsk (1995–2016). Infekciya i immunitet 2017; 5: 463 (in Russian).
- Upravlenie federal'noj sluzhby po nadzoru v sfere zashhity prav potrebitelej i blagopoluchija cheloveka po Permskomu kraju, available at: http://59.rospotrebnadzor.ru/265/-asset_publisher/y5CG/content (in Russian).
- On the state of sanitary and epidemiological well-being of the population in the Perm region in 2019: Gosudarstvennyj doklad. Federal'naya sluzhba po nadzoru v sfere zashchity prav potrebitelej i blagopoluchiya cheloveka, available at: http://59.rospotrebnadzor.ru/c/document_library/get_file?uuid=062a06bf-3224-4d55-92b6-b841b7358072&gro- upId=10156 (in Russian).
- Vorob'eva N.N. Clinic, treatment and prevention of ixodic tick-borne borreliosis. Perm'.: Ural-Press 1998; 136 (in Russian).
- Oborin M.S., Artamonova O.A. Theoretical aspects of the analysis of scientific works on the study of tick-borne infections. Antropogennaya transformaciya prirodnoj sredy 2015; 1: 51–57 (in Russian).
- Teterin V.YU., Korenberg E.I., Nefedo- va V.V., Vorob'eva N.N., Frizen V.I. Seronegative variant of erythemal form of ixodic tick-borne borreliosis. Zdorov'e naseleniya i sreda obitaniya 2012; 1 (226): 6–8 (in Russian).
- Emel'yanova A.N., Kalinina E.N., CHuprova G.A., Muratova E.A., Veselova E.V. Characteristics of some tick-borne vector-borne infections in Transbaikal. ZHurnal infektologii 2015; 7 (3): 34–35 (in Russian).
- Sokova E.A., Suzdal'cev A.A. Characteristics of patients with ixodic tick-borne borreliosis in the Samara region in 1999–2012. Infekcionnye bolezni 2013; 11 (prilozhenie 1): 371 (in Russian).
- Infectious diseases. Nacional'noe rukovodstvo. Pod red. N.D. Jushhuk, Ju.A. Vengerova. Moscow: GJeOTAR-Media 2019; 1104 (in Russian).
- Rahmanova A.G., Shcherbak N.YA., Kozlovskaya E.V., Andreeva N.V., Ulyukin I.M. Prevention of tick-borne encephalitis and ixodic tick-borne borreliosis in a megalopolis. Zdorov'e – osnova chelovecheskogo potenciala: problemy i puti ih resheniya 2015; 1: 404–405 (in Russian).
Supplementary files
