ASSESSMENT OF MORPHOLOGICAL ADENOID TISSUE CHANGES IN AGE ASPECT AMONG CHILDREN WITH DENTO-MAXILLARY ANOMALIES

Aim. To study the structural peculiarities of the adenoid tissue in children with dento-maxillary anomalies considered in age aspect as well as possible correlations. Materials and methods. Three groups of children were formed: group 1 - children aged 3 to 5 years, group 2-5 to 8 years, group 3-8 and older, who underwent surgical treatment of adenoid growth. Histological study of the ablated tissue was carried out. Results. In children of group 1, adenoid tissue structure provided the adaptation of local immune system to the exposure of local exogenous factors and formation of respiratory immune barrier that can be considered as a phase of formation of local immune barrier. In children of group 2, barrier function of epithelium was weakened in connection with focal squamous cell metaplasia. The symptoms of chronic inflammation with adequate reaction of lymphoid tissue and stress of immune response were noted. In group 3, persistence of microbial agents in crypts with inflammatory cells available was revealed. It was a symptom of chronic inflammation due to exhaustion of the local lymphoid tissue. Conclusions. Processes taking place in the structure of adenoids serve as a local immune response to the exposure of exogenous factors.

Adenoids, dento-maxillary anomalies, lymphoid tissue