Evaluation of the anti-inflammatory activity of melatonin in a model of experimental arthritis
- Authors: Naumov S.S.1
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Affiliations:
- Stavropol State Medical University
- Issue: Vol 19, No 1 (2021)
- Pages: 111-114
- Section: Short communications
- URL: https://journal-vniispk.ru/RCF/article/view/70656
- DOI: https://doi.org/10.17816/RCF191111-114
- ID: 70656
Cite item
Abstract
The epiphyseal hormone melatonin (1 and 5 mg/kg) significantly limited locomotor and psychoemotional disorders, indicators of inflammation and immunological reactivity in rats with experimental adjuvant arthritis.
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##article.viewOnOriginalSite##About the authors
Stanislav Sergeevich Naumov
Stavropol State Medical University
Author for correspondence.
Email: n_stanislav@mail.ru
SPIN-code: 4283-5843
Cand. Sci. (Med.)
Russian Federation, 310 Mira str., Stavropol, 355017References
- Arushanyan EB. Limitation of oxidative stress as the main factor of the universal protective properties of melatonin. Experimental and Clinical Pharmacology. 2012;75(5):44–49. (In Russ.)
- Arushanyan EB, Naumov SS. Anti-inflammatory potential of melatonin. Klinicheskaya meditsina. 2013;91(7):18–22. (In Russ.)
- Carrillo-Vico A, Lardone PJ, Alvarez-Sánchez N, et al. Melatonin: buffering the immune system. Int J Mol Sci. 2013;14(4):8638–8683. doi: 10.3390/ijms14048638
- Hardeland R. Melatonin and inflammation – Story of a double-edged blade. J Pineal Res. 2018;65(4): e12525. doi: 10.1111/jpi.12525
