Chorionic bump: ultrasound predictor of adverse pregnancy outcome
- Authors: Zheleznyak I.S.1, Ryazanov V.V.1,2, Sadykova G.K.1,2, Boykov I.V.1, Glebov S.G.2, Kuznetsova N.Y.3, Latysheva A.Y.1, Postanogov R.A.2
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Affiliations:
- Military Medical Academy
- Saint Petersburg State Pediatric Medical University
- Scientific Research Institute of Pulmonology
- Issue: Vol 42, No 3 (2023)
- Pages: 303-309
- Section: Reviews
- URL: https://journal-vniispk.ru/RMMArep/article/view/264769
- DOI: https://doi.org/10.17816/rmmar546120
- ID: 264769
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Abstract
For the first time R. Harris et al. in 2006 a chorionic bump was described, detected by ultrasound examination in the first trimester of pregnancy, having characteristic ultrasound signs and localization. Modern knowledge about the etiology and clinical significance of chorionic bump for predicting the outcome of pregnancy is insufficient and contradictory. Inconsistency of the data may be due to the rarity of occurrence, a small sample of the studied groups, the lack of histopathological studies. Among doctors who make ultrasound investigations there is a low awareness of chorionic bump and as a result an erroneous interpretation of sonography data. Nevertheless, there is more and more evidence that this sign is a predictor of an adverse outcome of pregnancy. Doctors who make ultrasound investigations in the first trimester of pregnancy should be aware of the chorionic bump and be able to differentiate it with other pathological conditions. If a chorionic bump is detected, ultrasound examination in dynamics should be recommended. Based on the study of domestic and foreign literature, this scientific review presents modern ideas about the pathomorphology of chorionic bump, informations about significance in terms of predicting the outcome of pregnancy, and the main aspects of ultrasound diagnostics and differential diagnosis of this pathology.
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##article.viewOnOriginalSite##About the authors
Igor S. Zheleznyak
Military Medical Academy
Email: igzh@bk.ru
ORCID iD: 0000-0001-7383-512X
SPIN-code: 1450-5053
M.D., D.Sc. (Medicine), Professor
Russian Federation, Saint PetersburgVladimir V. Ryazanov
Military Medical Academy; Saint Petersburg State Pediatric Medical University
Email: 79219501454@yandex.ru
ORCID iD: 0000-0002-0037-2854
SPIN-code: 2794-6820
M.D., D.Sc. (Medicine)
Russian Federation, Saint Petersburg; Saint PetersburgGulnaz K. Sadykova
Military Medical Academy; Saint Petersburg State Pediatric Medical University
Email: kokonya1980@mail.ru
ORCID iD: 0000-0002-6791-518X
SPIN-code: 3115-7430
M.D., Ph.D. (Medicine)
Russian Federation, Saint Petersburg; Saint PetersburgIgor V. Boykov
Military Medical Academy
Email: qwertycooolt@mail.ru
ORCID iD: 0000-0001-9594-9822
SPIN-code: 1453-8437
M.D., D.Sc. (Medicine); Professor
Russian Federation, Saint PetersburgSergey G. Glebov
Saint Petersburg State Pediatric Medical University
Email: sergey1990glebov@mail.ru
ORCID iD: 0009-0006-0446-5050
3rd year student
Russian Federation, Saint PetersburgNatalya Yu. Kuznetsova
Scientific Research Institute of Pulmonology
Email: kznnataly@mail.ru
ORCID iD: 0009-0005-1057-5048
M.D., Ph.D. (Medicine)
Russian Federation, MoscowAnastasiya Ya. Latysheva
Military Medical Academy
Email: vaska.petrova@yandex.ru
ORCID iD: 0000-0003-3677-8765
SPIN-code: 6793-1985
M.D., Ph.D. (Medicine)
Russian Federation, Saint PetersburgRoman A. Postanogov
Saint Petersburg State Pediatric Medical University
Author for correspondence.
Email: r.a.postanogov@yandex.ru
ORCID iD: 0000-0002-0523-9411
SPIN-code: 8686-1597
radiologist; address
Russian Federation, Saint PetersburgReferences
- Harris RD, Couto C, Karpovsky C, et al. The chorionic bump: a first-trimester pregnancy sonographic finding associated with a guarded prognosis. J Ultrasound Med. 2006;25(6):757–763. doi: 10.7863/jum.2006.25.6.757
- Arleo EK, Troiano RN. Chorionic bump on first-trimester sonography: not necessarily a poor prognostic indicator for pregnancy. J Ultrasound Med. 2015;34(1):137–142. doi: 10.7863/ultra.34.1.137
- Galleguillos C, Sepulveda W. Chorionic bump: Progression to a subamniotic hematoma. J Ultrasound Med. 2022;30(Pt 1):90–93. doi: 10.1177/1742271X211008565
- Yousaf A, Tayyab A, Anil MSU, et al. Chorionic Bump: Radiologic Features and Pregnancy Outcomes. Cureus. 2020;12(11): e11480. doi: 10.7759/cureus.11480
- Silva MC, Sepulveda-Martinez A, Guinez R, et al. Chorionic bump: an early ultras und marker for adverse obstetric outcome. Gynecol Obstet Invest. 2019;84(5):237–241. doi: 10.1159/000493477
- Altynnik NA, Medvedev MV, Voityuk EG. Chorial protrusion: analysis of 16 observations and literature review. Prenatal diagnostics. 2018;17(2):116–121. (In Russ.)
- Sana Y, Appiah A, Davison A, et al. Clinical significance of first-trimester chorionic bumps: a matched case-control study. Ultrasound Obstet Gynecol. 2013;42(5):585–589. doi: 10.1002/uog.12528
- Younesi L, Shahnazari R. Chorionic Bump in First-trimester Sonography. J Ultrasound Med. 2017;25(Pt 4):221–226. doi: 10.1016/j.jmu.2017.04.004
- Sepulveda W. Chorionic bump at 11 to 13 weeks’ gestation: Prevalence and clinical significance. Prenat Diagn. 2019;39(Pt 6): 471–476. doi: 10.1002/pd.5454
- Lu Y, Wu Y, Huang F, Ren M. A single-center retrospective study of the clinical significance of chorionic bump at early stage of gestation. Am J Reprod Immunol. 2021;85(3):e13346. doi: 10.1111/aji.13346
- Wax JR, Cartin A, Litton C, et al. First-trimester chorionic bump —Association with fetal aneuploidy in a high-risk population. J Clin Ultrasound. 2017;45(1):3–7. doi: 10.1002/jcu.22417
- Baalmann CG, Galgano SJ, Pietryga JA, et al. A Case of a Chorionic Bump: New Sonographic-Histopathologic Findings With Review of the Literature. J Ultrasound Med. 2017;36(Pt 9):1968–1970. doi: 10.1002/jum.14240.
- Carvalho RS, Osório M, Brito C, et al. Chorionic bump in a pregnant patient with a history of infertility. BMJ Case Rep. 2018;2018: bcr2018225091. doi: 10.1136/bcr-2018-225091
- Woodward PJ, Kennedy A, Sohaey R. Diagnosis Imaging: Obstetrics. Amsterdam: Elsevier Science; 2016. 1240 p.
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