Prophylactic antimicrobial drugs to pregnant women colonized with group B streptococcus

Group B streptococcus (GBS), Streptococcus agalactiae, are the causative agents of severe infection of the fetus and newborn child. The aim of the study was to evaluate the efficacy of antibacterial drugs in women in the III trimester of pregnancy for the prevention of B streptococcal infection. Studied during childbirth and the postpartum period, 70 women colonized by group B streptococcus, treated and not treated with antibacterial perparaty in the III trimester of pregnancy. Evaluated as a new-born children of these women. In pregnant women who received antibiotics in the III trimester of pregnancy, significantly fewer were delayed rupture of membranes, preterm labor, subinvolution uterus. Less common was marked asphyxia. Group B streptococcus significantly more frequently (in 43.5 % of cases) were identified in children born to mothers who did not receive antibiotics during pregnancy. In 26.1 % of these children diagnosed with intrauterine infection. Thus, the use of antimicrobials in the III trimester of pregnancy in detecting GBS in the urine in any quantity, simultaneous detection of these microorganisms in urine and vaginal discharge of a concentration of greater than 104 CFU/ml reduces the rate of preterm birth, postpartum complications, and neonatal asphyxia and intrauterine infection B streptococcal etiology.

group B streptococcus, colonization of newborns, intrauterine infection, antibiotic therapy