Cholestatic hepatosis in pregnant women: pathogenesis, symptoms, therapy.

This work studies causes, risk factors, features of the course and outcomes in 103 pregnant women with cholestatic hepatosis. The problem is significant due to the increased frequency of failure to carry the term and of perinatal pathology. Management tactics and methods for treating pregnant women with this pathology were developed. An analysis of the results indicated that including in complex therapeutic treatment of cholestatic hepatosis in pregnancy plasmapheresis and haemosorbtion increases the effectiveness of the treatment provided, improves clinico-laboratory parameters and aids to create optimal conditions for the prolongation of pregnancy and the reduction of perinatal complications.