Isulin-cortisol shifts in timely-temporal structure of functions in postmenopause

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Abstract

We screened serume levels of insulin and cortisol in 20 postmenopausal women. We performed these hormones determinations according to algorithm of their levels circaseptane oscillation. All examined patients did't complain on climacteric disorders and did't have any endocrinological diseases. We found out 5 types of hormone oscillations: when the concentrations of both hormones were at normal levels (5% cases); when insulin levels decreased from time to time (30% cases); when cortisol levels increased from time to time (35% cases); when during insulin levels' decreasing the cortisol levels has increased (25% cases); when both hormones levels increased from time to time.

About the authors

I. E. Zazerskaya

Ott Research Institute of Obstetrics and Gynecology, Russian Academy of Medical Sciences; Laboratory of Isotopic Research at the Vreden Russian Traumatology and Orthopedics Research Institute

Author for correspondence.
Email: info@eco-vector.com
Russian Federation, St. Petersburg; St. Petersburg

A. K. Ailamazyan

Ott Research Institute of Obstetrics and Gynecology, Russian Academy of Medical Sciences; Laboratory of Isotopic Research at the Vreden Russian Traumatology and Orthopedics Research Institute

Email: info@eco-vector.com
Russian Federation, St. Petersburg; St. Petersburg

N. V. Kornilov

Ott Research Institute of Obstetrics and Gynecology, Russian Academy of Medical Sciences; Laboratory of Isotopic Research at the Vreden Russian Traumatology and Orthopedics Research Institute

Email: info@eco-vector.com
Russian Federation, St. Petersburg; St. Petersburg

A. S. Avrunin

Ott Research Institute of Obstetrics and Gynecology, Russian Academy of Medical Sciences; Laboratory of Isotopic Research at the Vreden Russian Traumatology and Orthopedics Research Institute

Email: info@eco-vector.com
Russian Federation, St. Petersburg; St. Petersburg

A. M. Sukhanova

Ott Research Institute of Obstetrics and Gynecology, Russian Academy of Medical Sciences; Laboratory of Isotopic Research at the Vreden Russian Traumatology and Orthopedics Research Institute

Email: info@eco-vector.com
Russian Federation, St. Petersburg; St. Petersburg

References

Supplementary files

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2. Fig 1. Results of mathematical modeling of the dynamics of insulin and cortisol levels in the blood after orthopedic surgery. Horizontal axis - time after surgery (days); vertical axis - level of hormones in blood serum (nmol/L). A - dynamics of insulin level, B - dynamics of cortisol level.

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