Local cytokine production in patients with external genital endometriosis

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Abstract

The article presents the results of the investigation of cytokine production by endometrioid heterotopias in organotypic cultivation in comparison with the cell secretory activity of peritoneal fluid and endometrial tissue in women with external genital endometriosis.

The obtained results show systemic changes of regulation of cytokine production in the process of external genital endometriosis development.

About the authors

S. A. Selkov

Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott

Author for correspondence.
Email: info@eco-vector.com
Russian Federation, Saint Petersburg

N. L. Kramareva

Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott

Email: info@eco-vector.com
Russian Federation, Saint Petersburg

O. V. Pavlov

Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott

Email: info@eco-vector.com
Russian Federation, Saint Petersburg

М. I. Yarmolinskaya

Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott

Email: info@eco-vector.com
Russian Federation, Saint Petersburg

References

Supplementary files

Supplementary Files
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2. Figure 1. Content of IL-8 and IL-6 in supernatants of endometrioid heterotopies

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3. Figure 2. Content of IL-2, TNF and IL-10 in supernatants of endometrioid heterotopies

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4. Figure 3. The content of interleukin-1ß in the supernatants of endometrioid heterotopies depending on the prevalence of IGE

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5. Figure 4. IL-8 content in supernatants of endometrioid heterotopies depending on the prevalence of IGE

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6. Figure 5. IL-6 content in supernatants of endometrioid heterotopies depending on the prevalence of IGE

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7. Figure 6. IL-2 content in supernatants of endometrioid heterotopies depending on the prevalence of IGE

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8. Figure 7: Content of IL-8 and IL-6 in endometrial supernatants from patients with EGE

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9. Figure 8. Content of IL-2, TNF and IL-1β in endometrial supernatants from patients with EGE

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10. Figure 9. Content of IL-8 IL-8 and IL-6 in endometrial supernatants from patients with NFE and the control group

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11. Figure 10. Content of IL-ip, IL-2 and TNF in the supernatal endometrium of patients with EGE and the control group

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12. Figure 11. Content of IL-1ß, IL-6 and IL-8 in peritoneal fluid

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13. Figure 12. The content of IL-2 and TNF in the peritoneal fluid of patients

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