Dynamics of kininogenesis in patients with peptic ulcer disease against the background of drug therapy

Many aspects of pathogenesis, diagnostics and treatment of peptic ulcer disease continue to attract the attention of researchers. In pathogenesis of this disease a great role is given to biologically active substances, among which the most powerful are kinins. The revealed increase of kinin system activity in the acute period and its decrease in the remission period of peptic ulcer disease began to be considered as participation of this system in pathogenesis of the disease. There were developed recommendations on the use of antienzyme drugs (trasylol, contrical, etc.) in order to inhibit the activity of kallikrein-kinin system of blood in patients with this pathology.