The state of myocardial mast cells in atherosclerotic cardiosclerosis

In 1954, Constantmides and Cairns reported a relationship between the severity of atherosclerosis in coronary vessels and the number of mast cells in the myocardium. In the future, this issue has been repeatedly discussed, but the conclusions of various researchers are largely contradictory. Some authors [11, 14, 17] share this opinion, others [12, 13] do not find a connection between the number of mast cells and the severity of atherosclerosis. In later works carried out by domestic researchers (L. P. Ermilov, 1962; N. D. Kanshina, 1965), along with the number of mast cells in the connective tissue of the myocardium, their functional activity was studied for a number of morphological features. We have not found any works devoted to the histochemical study of mast cells in the myocardium in atherosclerosis.