Comorbid vaginal conditions in chronic cystitis
- Authors: Mustafina V.I.1, Sitdykova M.E.2
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Affiliations:
- Kazan Federal University
- Kazan State Medical University
- Issue: Vol 106, No 1 (2025)
- Pages: 17-25
- Section: Theoretical and clinical medicine
- URL: https://journal-vniispk.ru/kazanmedj/article/view/286121
- DOI: https://doi.org/10.17816/KMJ627640
- ID: 286121
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Abstract
BACKGROUND: Bacterial vaginosis is a significant risk factor for recurrent cystitis in women.
AIM: The study aimed to determine comorbid diseases as risk factors for recurrence of chronic cystitis.
METHODS: The study included 50 female patients. Group 1 included 25 women with chronic recurrent cystitis, whereas Group 2 consisted of 25 women with lower urinary tract symptoms and gynecological pathology. Vaginal microbiota was assessed by polymerase chain reaction (PCR). A clinical examination was conducted at the initial visit, on day 15, and on day 30 of treatment. A comparative analysis was performed using Student’s t-test (or, if applicable, Mann–Whitney U test). The data processing was executed using the Excel 2003 software package.
RESULTS: Bacteriuria was detected in 84% of patients in group 1, with Escherichia coli identified in 40% of patients. In group 2, bacteriuria was present in 64% of women. The PCR results in group 2 showed a predominance of pathogenic vaginal flora. By day 15, clinical improvement was achieved in 72% of patients in group 1. By day 30, treatment was completed by all 25 (100%) patients in this group. In contrast, by day 15, only 52% of women in group 2 reported positive trends, and by day 30, 36% continued treatment due to persistent symptoms.
CONCLUSION: Bacterial vaginosis with a predominance of opportunistic flora is a risk factor for recurrent lower urinary tract infections.
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##article.viewOnOriginalSite##About the authors
Venera I. Mustafina
Kazan Federal University
Author for correspondence.
Email: veneraish@mail.ru
ORCID iD: 0009-0007-6931-6002
SPIN-code: 5931-0080
MD, Cand. Sci. (Med.), Assoc. Prof., Depart. of Surgery
Russian Federation, 35 Kremlin street, 420008 KazanMarina E. Sitdykova
Kazan State Medical University
Email: marina-sitdykova@mail.ru
ORCID iD: 0000-0002-2183-443X
SPIN-code: 3794-8350
MD, Dr. Sci. (Med.), Prof., Head of Depart., Depart. of Urology named after E.N. Sitdykov
Russian Federation, KazanReferences
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