On the syphilitic hepatosplenic syndrome

Abstract

Hepatosplenic syndrome is one of those clinical concepts that have provided abundant ground for discussion and scientific research for many decades, and the essence of which cannot be considered fully clarified even now.

Already in the second half of the 19th century, Debov and Bruhl described pathological conditions where liver changes followed splenomegaly. In 1894, Banti described in detail an independent, in his opinion, disease affecting mainly young people, the etiology of which is not associated with syphilis, malaria, or any infectious diseases, as well as with chronic intoxication (alcohol); he called this disease - splenomegaly and cirrhosis of the liver.

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