Early experience of primary intestinal anastomosis in diverticular abscesses: a cohort study
- Authors: Karpukhin O.Y.1,2, Shakirov R.R.1,2, Pankratova Y.S.1,2
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Affiliations:
- Kazan State Medical University
- Republican Clinical Hospital, Kazan
- Issue: Vol 107, No 1 (2026)
- Pages: 141-149
- Section: Clinical experiences
- URL: https://journal-vniispk.ru/kazanmedj/article/view/382469
- DOI: https://doi.org/10.17816/KMJ684723
- EDN: https://elibrary.ru/JKSLLD
- ID: 382469
Cite item
Abstract
BACKGROUND: Over the last decade, studies have reported that primary colorectal anastomosis can be used to manage purulent inflammatory complications of diverticular disease. However, the indications for this intervention remain debatable.
AIM: To review early experiences with primary anastomosis for diverticular abscesses.
METHODS: The treatment outcomes of 58 patients with diverticular abscesses were studied. The evaluated abscesses were located in pericolic (32 [55.2%] patients), pelvic (19 [32.7%]), and distant sites (7 [12.1%]). Treatment included drug therapy, minimally invasive interventions, and combined surgical interventions. Treatment outcomes in 26 patients who underwent bowel resection with primary anastomosis and 11 patients who underwent Hartmann’s procedure were compared. Significant differences were assessed using Fisher’s exact test and Student’s t-test for independent samples using the GraphPad QuickCalcs online calculator based on standard statistical analysis algorithms.
RESULTS: Primary anastomosis was performed in 12 patients (37.5%) with pericolic abscesses, 11 patients (57.9%) with pelvic abscesses, and 3 patients (42.9%) with distant abscesses. The surgical option was selected based on the abscess’ location and extent and the patient’s condition, age, and comorbidities. In patients with primary diverticular abscesses who underwent urgent surgeries, anastomosis was conducted in 10 of 21 (47.6%) patients, and in all 16 patients with recurrent abscesses. Young and middle-aged individuals (55.5 ± 9.42 years) predominated in the primary anastomosis group, while elderly and senile individuals (71.6 ± 8.94 years) predominated in the stoma group. Bowel resection, although more technically complex than Hartmann’s procedure, showed no significant increase in complications (p = 0.119) and resulted in less severe outcomes.
CONCLUSION: Primary anastomosis for diverticular abscesses is a surgical option for young and middle-aged individuals without comorbidities and generalized inflammation.
About the authors
Oleg Yu. Karpukhin
Kazan State Medical University; Republican Clinical Hospital, Kazan
Author for correspondence.
Email: oleg_karpukhin@mail.ru
ORCID iD: 0000-0002-7479-4945
SPIN-code: 7272-8878
MD, Dr. Sci. (Medicine), Professor, Depart. of Surgical Diseases; Advis. Сurator, Depart. of Coloproctology
Russian Federation, Kazan; KazanRais R. Shakirov
Kazan State Medical University; Republican Clinical Hospital, Kazan
Email: raiskazan2@mail.ru
ORCID iD: 0000-0001-8344-2696
SPIN-code: 2570-6193
Assistant Lecturer, Depart. of Surgical Diseases; physician, Depart. of Coloproctology
Russian Federation, Kazan; KazanYulia S. Pankratova
Kazan State Medical University; Republican Clinical Hospital, Kazan
Email: iuliiaps@gmail.com
ORCID iD: 0000-0001-7498-2412
SPIN-code: 1511-6583
MD, Cand. Sci. (Medicine), Assistant Lecturer, Depart. of Surgical Diseases; physician, Depart. of Surgery No. 1
Russian Federation, Kazan; KazanReferences
- Sohn M, Agha A, Iesalnieks I, et al. Risk of colectomy after conservative treatment of diverticulitis of the left hemicolon complicated by abdominal or pelvic abscess: protocol of a systematic review and meta-analysis. BMJ Open. 2020;10(12):e042350. doi: 10.1136/bmjopen-2020-042350 EDN: RZAHBY
- Tănase I, Păun S, Stoica B, et al. Epidemiology of diverticular disease — systematic review of the literature. Chirurgia. 2015;110(1):9–14. Available from: http://revistachirurgia.ro/pdfs/2015-1-9.pdf
- Podda M, Ceresoli M, Di Martino M, et al. Towards a tailored approach for patients with acute diverticulitis and abscess formation. The DivAbsc2023 multicentre case-control study. Surg Endosc. 2024;38(6):3180–3194. doi: 10.1007/s00464-024-10793-z
- Gregersen R, Mortensen LQ, Burcharth J, et al. Treatment of patients with acute colonic diverticulitis complicated by abscess formation: A systematic review. Int J Surg. 2016;35:201–208. doi: 10.1016/j.ijsu.2016.10.006
- Mali J, Mentula P, Leppäniemi A, Sallinen V. Determinants of treatment and outcomes of diverticular abscesses. World J Emerg Surg. 2019;14:31. doi: 10.1186/s13017-019-0250-5
- Lamb MN, Kaiser AM. Elective resection versus observation after nonoperative management of complicated diverticulitis with abscess: a systematic review and meta-analysis. Dis Colon Rectum. 2014;57(12):1430–1440. doi: 10.1097/DCR.0000000000000230
- Tursi A, Elisei W. Role of Inflammation in the Pathogenesis of Diverticular Disease. Mediators Inflamm. 2019;2019:8328490. doi: 10.1155/2019/8328490
- Achkasov SI, Likhter MI, Moskalev AI, et al. Diverticular disease complicated by colovesical fistulas. Surgery Eastern Europe. 2024;13(4):472–480. doi: 10.34883/PI.2024.13.4.013 EDN: OCSCZT
- Ilkanich AYa, Bidzheva YuKh, Edchik RA, Giniyatullina LF. Surgical treatment of complications of diverticular disease and conditions related to it. In: Fundamental and applied problems of human health in the north. Collection of materials of the VI All-Russian scientific and practical conference. Isaev AA, editor. Surgut: Surgut State University; 2022. P. 85–89. EDN: ZHTBEC
- Chiu A, Chan HT, Brown CJ, et al. Failing to reverse a diverting stoma after lower anterior resection of rectal cancer. Am J Surg. 2014;207(5):708–711; discussion 711. doi: 10.1016/j.amjsurg.2013.12.016
- McChesney SL, Hawkins AT. Anastomotic Considerations in Diverticulitis. Clin Colon Rectal Surg. 2022;36(1):57–62. doi: 10.1055/s-0042-1756511
- Evidence review for primary versus secondary anastomosis (timing of anastomosis) in complicated acute diverticulitis. Diverticular disease: diagnosis and management. London: National Institute for Health and Care Excellence (UK); 2019. 147 p.
- Karpukhin OYu, Yusupova AF, Pankratova YuS, et al. Computer tomography in diagnostics and treatment of inflammatory complications of diverticular disease of the colon. Koloproktologia. 2021;20(4):34–41. doi: 10.33878/2073-7556-2021-20-4-34-41 EDN: LYJIRL
- Shelygin YuA, Ivashkin VT, Achkasov SI, et al. Clinical guidelines Diverticular disease (57.2, 57.3), adults. Koloproktologia. 2024;23(2):10–27. doi: 10.33878/2073-7556-2024-23-2-10-27 EDN: JSKYYA
- Lambrichts DP, Edomskis PP, van der Bogt RD, et al. Sigmoid resection with primary anastomosis versus the Hartmann's procedure for perforated diverticulitis with purulent or fecal peritonitis: a systematic review and meta-analysis. Int J Colorectal Dis. 2020;35(8):1371–1386. doi: 10.1007/s00384-020-03617-8
- Reid TD, Shrestha R, Stone L, et al. Socioeconomic disparities in ostomy reversal among older adults with diverticulitis are more substantial among non-Hispanic Black patients. Surgery. 2021;170(4):1039–1046. doi: 10.1016/j.surg.2021.03.050
- Pankratova YuS, Karpukhin OYu, Ziganshin MI, Shakurov AF. Colonic invagination anastomosis in surgery of complicated forms of diverticular disease. Koloproktologia. 2021;20(4):42–48. doi: 10.33878/2073-7556-2021-20-4-42-48 EDN: LESSWX
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