About diagnosis and therapy of mmunohematological diseases

Having received wide development since the 40s, immunohematology has now acquired great practical importance in the diagnosis and treatment of many diseases of the blood and internal organs. The long-standing dispute between II Mechnikov and P. Ehrlich about the possibility of the appearance in the body of autoantibodies active against their own proteins of cells and tissues was resolved in favor of II Mechnikov. Moreover, it has now become generally accepted that these antibodies are often auto-aggressive, leading to destruction, damage or dysfunction of the cells and tissues against which they are directed. Diseases in the pathogenesis of which the process of autoimmunization plays a role are called autoimmune, autoaggressive, or autoallergic. These include diseases of the blood system such as chronic acquired hemolytic anemia (idiopathic and symptomatic), some types of idiopathic and symptomatic leukopenias and thrombocytopenic purpura, allergic (drug) cytopenias, as well as a number of diseases of other organs (systemic lupus erythematosus, Hashimoto's disease and others ).